Search markers
Conditions
- Alzheimer's Disease and Other Dementias3 markers · ↑3 ↓0 ↕0 · jump to list
- Asthma4 markers · ↑4 ↓0 ↕0 · jump to list
- Atrial Fibrillation3 markers · ↑3 ↓0 ↕0 · jump to list
- Chronic Kidney Disease6 markers · ↑5 ↓1 ↕0 · jump to list
- COPD5 markers · ↑2 ↓3 ↕0 · jump to list
- Epilepsy3 markers · ↑3 ↓0 ↕0 · jump to list
- GERD (Gastroesophageal Reflux Disease)2 markers · ↑2 ↓0 ↕0 · jump to list
- Gulf War Illness41 markers · ↑17 ↓9 ↕15 · jump to list
- Hepatitis C4 markers · ↑4 ↓0 ↕0 · jump to list
- Hypertension3 markers · ↑3 ↓0 ↕0 · jump to list
- Hypothyroidism5 markers · ↑3 ↓2 ↕0 · jump to list
- Inflammatory Bowel Disease (Crohn's/UC)5 markers · ↑5 ↓0 ↕0 · jump to list
- Long COVID77 markers · ↑50 ↓14 ↕13 · jump to list
- Low Back Pain2 markers · ↑2 ↓0 ↕0 · jump to list
- Lyme Disease36 markers · ↑23 ↓2 ↕11 · jump to list
- Major Depressive Disorder4 markers · ↑3 ↓1 ↕0 · jump to list
- ME/CFS46 markers · ↑16 ↓17 ↕13 · jump to list
- Migraine2 markers · ↑1 ↓1 ↕0 · jump to list
- Multiple Sclerosis4 markers · ↑4 ↓0 ↕0 · jump to list
- NAFLD / MASH (Metabolic-Associated Steatohepatitis)5 markers · ↑5 ↓0 ↕0 · jump to list
- Osteoarthritis5 markers · ↑4 ↓1 ↕0 · jump to list
- PACVS32 markers · ↑16 ↓11 ↕5 · jump to list
- Rheumatoid Arthritis5 markers · ↑5 ↓0 ↕0 · jump to list
- Type 1 Diabetes6 markers · ↑5 ↓1 ↕0 · jump to list
- Type 2 Diabetes6 markers · ↑5 ↓1 ↕0 · jump to list
Cross-condition marker hubs (236)
- CRP (11 conditions)
- Interleukin-6 (IL-6) (8 conditions)
- Neurofilament light chain (NfL) (5 conditions)
- Cortisol (4 conditions)
- Heart rate variability (HRV) (4 conditions)
- Interleukin-8 (IL-8 / CXCL8) (4 conditions)
- 6-minute walk distance (3 conditions)
- ALT (3 conditions)
- Anti-GPCR autoantibodies (panel) (3 conditions)
- ESR (3 conditions)
- Ferritin (3 conditions)
- Interleukin-1 (IL-1α/β) (3 conditions)
- Interleukin-10 (IL-10) (3 conditions)
- Lactate (3 conditions)
- NT-proBNP (3 conditions)
- Orthostatic heart rate increment (3 conditions)
- S100B (3 conditions)
- sCD14 (3 conditions)
- Tumor Necrosis Factor-α (TNF-α) (3 conditions)
- Acylcarnitines (composite) (2 conditions)
- AST (2 conditions)
- ATP (plasma) (2 conditions)
- Brain-derived neurotrophic factor (BDNF) (2 conditions)
- Ceramides (plasma) (2 conditions)
- CSF Oligoclonal Bands (2 conditions)
- D-dimer (2 conditions)
- Fasting Plasma Glucose (2 conditions)
- Fibrinogen (2 conditions)
- GFAP (2 conditions)
- HbA1c (2 conditions)
- Interferon-γ (IFN-γ) (2 conditions)
- Kynurenine (2 conditions)
- Resistin (2 conditions)
- Rheumatoid factor (RF) (2 conditions)
- Sarcosine (2 conditions)
- Serine (2 conditions)
- Transforming Growth Factor-β (TGF-β) (2 conditions)
- Urinary Albumin-Creatinine Ratio (2 conditions)
- Vitamin D (25-OH) (2 conditions)
- β2-adrenergic receptor autoantibodies (2 conditions)
- 2-day CPET VO₂ peak (day 2) (1 condition)
- 2P proteotypic peptides (K986P/V987P) (1 condition)
- 4-Aminobutanoate (GABA) (1 condition)
- 5-Aminolevulinate (1 condition)
- 5-Hydroxykynurenine (1 condition)
- 8-isoprostane (1 condition)
- Acetylcholinesterase (AChE) (1 condition)
- Acute phase proteins (1 condition)
- Adiponectin (1 condition)
- Aldosterone (1 condition)
- Alpha-1 Antitrypsin (1 condition)
- Amyloid-fibrin microclots (1 condition)
- Anaplasma phagocytophilum serology (1 condition)
- ANCA Antibodies (1 condition)
- Anti-ACE2 autoantibodies (1 condition)
- Anti-acetylcholine receptor antibodies (1 condition)
- Anti-ADRA2A (α2B adrenergic receptor) (1 condition)
- Anti-AT1R (angiotensin II type 1 receptor) (1 condition)
- Anti-Bb IgG (synovial PCR) (1 condition)
- Anti-CCP Antibodies (1 condition)
- Anti-CHRM3 (muscarinic M3) (1 condition)
- Anti-idiotype antibodies (ACE2 ↔ Anti-S) (1 condition)
- Anti-IFN-α autoantibodies (1 condition)
- Anti-IFN-ω autoantibodies (1 condition)
- Anti-MAS1 receptor autoantibodies (1 condition)
- Anti-neuronal antibodies (PTLDS) (1 condition)
- Anti-nuclear antibodies (ANA) (1 condition)
- Anti-Nucleocapsid (Anti-N) antibodies (1 condition)
- Anti-OspA antibodies (1 condition)
- Anti-OspC antibodies (1 condition)
- Anti-p41 (flagellin) antibodies (1 condition)
- Anti-Spike (Anti-S) antibodies (1 condition)
- Anti-STAB1 autoantibodies (1 condition)
- Anti-Thyroglobulin Antibodies (1 condition)
- Anti-TPO Antibodies (1 condition)
- Anti-VlsE antibodies (1 condition)
- Arginine (1 condition)
- ASCA Antibodies (1 condition)
- Asparagine (1 condition)
- Aspartate (1 condition)
- Asymmetric dimethylarginine (ADMA) (1 condition)
- ATP production capacity (1 condition)
- B. burgdorferi culture (1 condition)
- B. burgdorferi EIA (screening) (1 condition)
- B. burgdorferi PCR (blood/CSF/tissue) (1 condition)
- Babesia microti serology / PCR (1 condition)
- Baroreflex sensitivity (1 condition)
- Blood Eosinophil Count (1 condition)
- Blood lactate (exercise) (1 condition)
- Blood pressure variability (1 condition)
- BNT162b2 vaccine mRNA (qPCR) (1 condition)
- Butyrylcholinesterase (BChE) (1 condition)
- C-Peptide (1 condition)
- C16 Acylcarnitine (palmitoylcarnitine) (1 condition)
- C18 Acylcarnitine (stearoylcarnitine) (1 condition)
- C6 peptide ELISA (VisE) (1 condition)
- Calcitonin Gene-Related Peptide (CGRP) (1 condition)
- Carnitine / Acylcarnitines (1 condition)
- Cartilage Oligomeric Matrix Protein (COMP) (1 condition)
- CCL19 (1 condition)
- CCL4 (MIP-1β) (1 condition)
- CD26 / sCD26 (DPPIV) (1 condition)
- CD8+ T cell perforin (1 condition)
- Chester Step Test (VO₂ proxy) (1 condition)
- Circulating spike (post-mRNA myocarditis) (1 condition)
- Coagulation cascade proteins (1 condition)
- Coenzyme Q10 (1 condition)
- Complement C3a / C5a (1 condition)
- Complement cascade proteins (1 condition)
- Contrast sensitivity (1 condition)
- CSF anti-Bb antibody index (1 condition)
- CSF CXCL13 (1 condition)
- CSF glucose (1 condition)
- CSF IgG Index (1 condition)
- CSF lymphocytic pleocytosis (1 condition)
- CSF protein elevation (1 condition)
- Cystatin C (1 condition)
- Cystatin D (CST5) (1 condition)
- Cytokeratin-18 (CK-18) (1 condition)
- Depleted uranium (urinary) (1 condition)
- DHEA / DHEA-S (1 condition)
- DNA adducts (pesticide-related) (1 condition)
- ECM remodeling proteins (1 condition)
- eGFR (1 condition)
- Ehrlichia / Ehrlichiosis panel (1 condition)
- EM skin biopsy PCR (1 condition)
- Endothelin-1 (1 condition)
- Esophageal Acid Exposure Time (1 condition)
- Exertional SpO₂ nadir (1 condition)
- Facial palsy + CSF pleocytosis (1 condition)
- Faecalibacterium prausnitzii (1 condition)
- Fasting Insulin (1 condition)
- Fecal Calprotectin (1 condition)
- FEV1 (1 condition)
- FEV1/FVC ratio (1 condition)
- FIB-4 Index (1 condition)
- Flt-1 / sVEGFR-1 (1 condition)
- Fractional Exhaled Nitric Oxide (FeNO) (1 condition)
- Free carnitine (1 condition)
- Free T3 (1 condition)
- Free T4 (1 condition)
- GAD65 autoantibodies (1 condition)
- GGT (1 condition)
- Glutamine (1 condition)
- Glutathione (GSH) (1 condition)
- GSH:GSSG ratio (1 condition)
- Gut microbiome alpha diversity (1 condition)
- H3K9Ac (chromatin marker) (1 condition)
- HCV RNA Viral Load (1 condition)
- Histidine (1 condition)
- Homocysteine (1 condition)
- hsCRP (1 condition)
- Hyaluronic Acid (1 condition)
- IA-2 autoantibodies (1 condition)
- ICAM-1 (1 condition)
- IgG immunoblot (≥5 of 10 bands) (1 condition)
- IgM immunoblot (≥2 of 3 bands) (1 condition)
- Laser-induced blood spectra (LIBS) (1 condition)
- LDH (Lactate dehydrogenase) (1 condition)
- Leptin (1 condition)
- LF/HF ratio (1 condition)
- Low naive T cells / High effector memory (1 condition)
- Lyme arthritis RF/anti-CCP (1 condition)
- Lysophosphatidylcholines (1 condition)
- Macular pigment optical density (1 condition)
- Mitochondrial membrane potential (1 condition)
- MMP-3 (1 condition)
- Muscarinic cholinergic autoantibodies (1 condition)
- Muscarinic receptor autoantibodies (1 condition)
- Neopterin (1 condition)
- Neuron-Specific Enolase (NSE) (1 condition)
- Neutrophil elastase (1 condition)
- NK cell cytotoxicity (1 condition)
- Opportunistic pathogens (1 condition)
- Oxidative phosphorylation efficiency (1 condition)
- PAC-19QoL score (1 condition)
- PAI-1 (1 condition)
- Parathyroid Hormone (1 condition)
- PBMC cytokine profile (PTLDS) (1 condition)
- Periostin (1 condition)
- Phosphatidylcholines (1 condition)
- Phosphorylated Tau (p-tau181) (1 condition)
- Platelet hyperactivation (1 condition)
- PON1 (paraoxonase 1) activity (1 condition)
- PON1 Q192R polymorphism (1 condition)
- Porphobilinogen (1 condition)
- Powassan virus serology (1 condition)
- Pro-inflammatory cytokines (composite) (1 condition)
- Prolactin (1 condition)
- Putrescine (1 condition)
- Pyruvate dehydrogenase activity (1 condition)
- RNase L (37-kDa fragment) (1 condition)
- S1 in CD16+ monocytes (1 condition)
- Salivary nitric oxide (1 condition)
- Salivary Pepsin (1 condition)
- Sarin/cyclosarin exposure markers (1 condition)
- SARS-CoV-2 RNA (1 condition)
- SARS-CoV-2 spike protein (1 condition)
- sCD26 (soluble DPPIV) (1 condition)
- Serotonin (1 condition)
- Serum Amyloid A (SAA) (1 condition)
- Serum Creatinine (1 condition)
- Serum CXCL13 (PTLDS research) (1 condition)
- Serum Magnesium (1 condition)
- Serum Phosphate (1 condition)
- SF-36 physical component score (1 condition)
- SF-36 physical function score (1 condition)
- Short-chain fatty acids (SCFAs) (1 condition)
- Sphingolipid species (1 condition)
- Spike (LC-MS/MS quantification) (1 condition)
- Spike in cutaneous lesions (1 condition)
- Spike in neurological tissue (1 condition)
- Synovial fluid anti-Bb antibodies (1 condition)
- T cell exhaustion markers (1 condition)
- Tau protein (1 condition)
- TCA cycle intermediates (1 condition)
- Thrombin-antithrombin complex (1 condition)
- Thymine (1 condition)
- Total IgE (1 condition)
- Total Tau (1 condition)
- Transferrin saturation (1 condition)
- Triglycerides (1 condition)
- Troponin (1 condition)
- TSH (1 condition)
- Uracil (1 condition)
- Urinary creatinine-normalized metabolites (1 condition)
- Urinary CTX-II (1 condition)
- Urinary metabolite panel (1 condition)
- Vaccine mRNA (hybrid 3'UTR motifs) (1 condition)
- VCAM-1 (1 condition)
- von Willebrand Factor (vWF) (1 condition)
- Wild-type viral spike peptides (1 condition)
- Workload at anaerobic threshold (1 condition)
- Xanthine (1 condition)
- ZnT8 autoantibodies (1 condition)
- β2-microglobulin (1 condition)
Alzheimer's Disease and Other Dementias (3 markers)
Open the Alzheimer's Disease and Other Dementias atlas
Neurological
Asthma (4 markers)
Pulmonary
Atrial Fibrillation (3 markers)
Open the Atrial Fibrillation atlas
Cardiac
Inflammatory
- CRP ↑
Chronic Kidney Disease (6 markers)
Open the Chronic Kidney Disease atlas
Renal
COPD (5 markers)
Inflammatory
- CRP ↑
- Fibrinogen ↑
Pulmonary
Epilepsy (3 markers)
Neurological
GERD (Gastroesophageal Reflux Disease) (2 markers)
Open the GERD (Gastroesophageal Reflux Disease) atlas
Gastrointestinal
Gulf War Illness (41 markers)
Open the Gulf War Illness atlas
Autoimmune
- Anti-acetylcholine receptor antibodies ↑
- Anti-nuclear antibodies (ANA) ↕
- Rheumatoid factor (RF) ↕
- β2-adrenergic receptor autoantibodies ↑
- Muscarinic receptor autoantibodies ↑
Autonomic
Exposure
- PON1 (paraoxonase 1) activity ↓
- PON1 Q192R polymorphism ↕
- Butyrylcholinesterase (BChE) ↕
- Acetylcholinesterase (AChE) ↕
- DNA adducts (pesticide-related) ↑
- Depleted uranium (urinary) ↕
- Sarin/cyclosarin exposure markers ↕
Functional
Inflammatory
- C-Reactive Protein (CRP) ↑
- Tumor Necrosis Factor-α (TNF-α) ↑
- Interleukin-6 (IL-6) ↑
- Interleukin-1β (IL-1β) ↑
- Interleukin-8 (IL-8 / CXCL8) ↑
- Neopterin ↑
- sCD26 (soluble DPPIV) ↕
- sCD14 ↑
- Interferon-γ (IFN-γ) ↑
- H3K9Ac (chromatin marker) ↕
Metabolic
- Homocysteine ↑
- Glutathione (GSH) ↓
- GSH:GSSG ratio ↓
- 8-isoprostane ↑
- Coenzyme Q10 ↓
- Acylcarnitines ↑
- Lactate ↑
- Vitamin D (25-OH) ↕
Neurological
Ocular
Hepatitis C (4 markers)
Hepatic
Hypertension (3 markers)
Cardiac
Endocrine
Renal
Hypothyroidism (5 markers)
Endocrine
Inflammatory Bowel Disease (Crohn's/UC) (5 markers)
Open the Inflammatory Bowel Disease (Crohn's/UC) atlas
Immune
Inflammatory
Long COVID (77 markers)
Coagulation
- D-dimer ↑
- Fibrinogen ↑
- PAI-1 ↑
- Amyloid-fibrin microclots ↑
- Platelet hyperactivation ↑
- Thrombin-antithrombin complex ↑
Immune
- Anti-IFN-α autoantibodies ↑
- Anti-IFN-ω autoantibodies ↑
- Anti-GPCR autoantibodies ↑
- β2-microglobulin ↑
- Complement C3a / C5a ↑
- T cell exhaustion markers ↑
- Low naive T cells / High effector memory ↕
Inflammatory
- Interleukin-6 (IL-6) ↑
- Tumor Necrosis Factor-α (TNF-α) ↑
- Interleukin-1α (IL-1α) ↑
- C-Reactive Protein (CRP) ↑
- Soluble CD14 (sCD14) ↑
- Flt-1 / sVEGFR-1 ↑
- CCL4 (MIP-1β) ↑
- Cystatin D (CST5) ↑
- Pro-inflammatory cytokines (composite) ↓
- Transforming Growth Factor-β (TGF-β) ↑
- Interleukin-8 (IL-8) ↑
- Interleukin-10 (IL-10) ↕
- Ferritin ↕
- Serum Amyloid A (SAA) ↑
Lipidomic
Metabolic
- ATP (plasma) ↓
- Serine ↓
- Sarcosine ↓
- Aspartate ↓
- Asparagine ↓
- Glutamine ↓
- Arginine ↓
- Histidine ↓
- TCA cycle intermediates ↑
- Kynurenine ↑
- 5-Hydroxykynurenine ↑
- Serotonin ↑
- Putrescine ↑
- 5-Aminolevulinate ↑
- Porphobilinogen ↑
- Uracil ↓
- Thymine ↓
- Xanthine ↑
- 4-Aminobutanoate (GABA) ↑
- Lactate ↑
- Carnitine / Acylcarnitines ↕
- LDH (Lactate dehydrogenase) ↑
- Vitamin D (25-OH) ↕
Microbiome
- Gut microbiome alpha diversity ↓
- Faecalibacterium prausnitzii ↓
- Short-chain fatty acids (SCFAs) ↕
- Opportunistic pathogens ↑
Neurological
Proteomic
- Complement cascade proteins ↑
- Coagulation cascade proteins ↑
- Acute phase proteins ↑
- ECM remodeling proteins ↕
- Cortisol ↕
Vascular
- von Willebrand Factor (vWF) ↑
- ICAM-1 ↑
- VCAM-1 ↑
- Resistin ↑
- Endothelin-1 ↑
- Asymmetric dimethylarginine (ADMA) ↑
- NT-proBNP ↑
- Troponin ↑
Viral
Low Back Pain (2 markers)
Inflammatory
Lyme Disease (36 markers)
CSF
- CSF CXCL13 ↑
- CSF anti-Bb antibody index ↑
- CSF lymphocytic pleocytosis ↑
- CSF protein elevation ↑
- CSF oligoclonal bands ↕
- CSF glucose ↕
Chronic/PTLDS
- Serum CXCL13 (PTLDS research) ↕
- PBMC cytokine profile (PTLDS) ↕
- Anti-neuronal antibodies (PTLDS) ↕
- Heart rate variability (PTLDS) ↓
Co-infection
- Anaplasma phagocytophilum serology ↑
- Babesia microti serology / PCR ↑
- Ehrlichia / Ehrlichiosis panel ↑
- Powassan virus serology ↑
Functional
Inflammatory
- Interleukin-6 (IL-6) ↑
- Interleukin-10 (IL-10) ↑
- Interferon-γ (IFN-γ) ↑
- C-Reactive Protein (CRP) ↕
- CCL19 ↑
- ESR (erythrocyte sedimentation rate) ↕
Molecular
- B. burgdorferi PCR (blood/CSF/tissue) ↕
- B. burgdorferi culture ↕
- EM skin biopsy PCR ↑
- Anti-Bb IgG (synovial PCR) ↕
Serologic
Major Depressive Disorder (4 markers)
Open the Major Depressive Disorder atlas
Endocrine
- Cortisol ↑
Inflammatory
Neurological
- BDNF ↓
ME/CFS (46 markers)
Autoimmune
- β2-adrenergic receptor autoantibodies ↑
- Muscarinic cholinergic autoantibodies ↑
- Anti-GPCR autoantibodies (panel) ↑
Autonomic
- Heart rate variability (RMSSD) ↓
- Heart rate variability (SDNN) ↓
- LF/HF ratio ↕
- Orthostatic heart rate increment ↑
- Blood pressure variability ↑
- Baroreflex sensitivity ↓
Functional
- 2-day CPET VO₂ peak (day 2) ↓
- Workload at anaerobic threshold ↓
- 6-minute walk distance ↓
- SF-36 physical function score ↓
Immune
- NK cell cytotoxicity ↓
- CD8+ T cell perforin ↓
- RNase L (37-kDa fragment) ↑
- Neutrophil elastase ↑
- CD26 / sCD26 (DPPIV) ↕
Inflammatory
- Interleukin-1 (IL-1α/β) ↑
- Transforming Growth Factor-β (TGF-β) ↑
- Tumor Necrosis Factor-α (TNF-α) ↕
- Interleukin-6 (IL-6) ↕
- Interleukin-8 (IL-8 / CXCL8) ↕
- Interleukin-10 (IL-10) ↕
- C-Reactive Protein (CRP) ↕
- Leptin ↑
- Resistin ↕
- sCD14 ↑
Metabolic
- Acylcarnitines (composite) ↑
- C16 Acylcarnitine (palmitoylcarnitine) ↑
- C18 Acylcarnitine (stearoylcarnitine) ↑
- Free carnitine ↕
- Lactate (blood) ↑
- Serine ↓
- Sarcosine ↓
- Kynurenine ↑
- Ceramides (plasma) ↓
- ATP (plasma) ↓
Mitochondrial
- ATP production capacity ↓
- Mitochondrial membrane potential ↓
- Pyruvate dehydrogenase activity ↓
- Oxidative phosphorylation efficiency ↓
Neurological
Urinary
Migraine (2 markers)
Neurological
Multiple Sclerosis (4 markers)
Open the Multiple Sclerosis atlas
Neurological
Other
NAFLD / MASH (Metabolic-Associated Steatohepatitis) (5 markers)
Open the NAFLD / MASH (Metabolic-Associated Steatohepatitis) atlas
Hepatic
- ALT ↑
- AST ↑
- Cytokeratin-18 (CK-18) ↑
- GGT ↑
Other
- Ferritin ↑
Osteoarthritis (5 markers)
Inflammatory
- CRP ↑
Musculoskeletal
PACVS (32 markers)
Autoimmune
- Anti-ACE2 autoantibodies ↑
- Anti-AT1R (angiotensin II type 1 receptor) ↑
- Anti-MAS1 receptor autoantibodies ↑
- Anti-STAB1 autoantibodies ↑
- Anti-ADRA2A (α2B adrenergic receptor) ↓
- Anti-CHRM3 (muscarinic M3) ↕
- Anti-idiotype antibodies (ACE2 ↔ Anti-S) ↕
- Anti-GPCR autoantibodies (panel) ↑
Functional
- Heart rate variability (HRV) ↓
- Salivary nitric oxide ↓
- Orthostatic heart rate increment ↑
- 6-minute walk distance ↓
- Exertional SpO₂ nadir ↓
- Chester Step Test (VO₂ proxy) ↓
- PAC-19QoL score ↓
- Neurofilament light chain (NfL) ↑
Inflammatory
Metabolic
Molecular
- 2P proteotypic peptides (K986P/V987P) ↑
- Wild-type viral spike peptides ↓
- BNT162b2 vaccine mRNA (qPCR) ↕
- Vaccine mRNA (hybrid 3'UTR motifs) ↕
Proteomic
Serologic
Spike Antigen
Rheumatoid Arthritis (5 markers)
Open the Rheumatoid Arthritis atlas
Immune
Inflammatory
Type 1 Diabetes (6 markers)
Open the Type 1 Diabetes atlas
Metabolic
Type 2 Diabetes (6 markers)
Open the Type 2 Diabetes atlas
Inflammatory
- hsCRP ↑
Metabolic
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Generated 2026-10-07 from the atlas JSON files. See also the cross-condition Biomarker Index and the Biomarker Atlas hub.