Where Pyruvate dehydrogenase activity is reported
Also listed as: PDH complex
| Condition | Direction | Compared against | Associated symptoms | Source |
|---|---|---|---|---|
| ME/CFS | ↓ reduced | healthy controls | Aerobic metabolism impairment | Holden et al. 2020 |
Frequently asked questions
In which conditions is Pyruvate dehydrogenase activity altered?
In the OSMF atlas Pyruvate dehydrogenase activity is reported in ME/CFS. It is reduced in 1 across 1 entries.
Is there a standard clinical test for Pyruvate dehydrogenase activity?
The atlas entries for Pyruvate dehydrogenase activity do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.
Is one abnormal Pyruvate dehydrogenase activity result diagnostic?
No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas
Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.