Last updated 07 October 2026 from ClinicalTrials.gov. Trial statuses are refreshed automatically; check the registry record for the latest status and contact details.
These pages are rebuilt automatically from ClinicalTrials.gov so that patients, clinicians and researchers can see which post-viral trials are open right now, which have finished, and which interventions have been tested. Each trial links directly to its registry record. OSMF does not run any of these trials.
Recruiting Long COVID trials
Trials currently recruiting, not yet recruiting or enrolling by invitation, grouped by status and phase.
Recruiting ME/CFS trials
Trials currently recruiting, not yet recruiting or enrolling by invitation, grouped by status and phase.
Recruiting post-viral overlap trials
Trials currently recruiting, not yet recruiting or enrolling by invitation, grouped by status and phase.
Trials by therapeutic agent
One page per intervention tested in two or more trials. Most trialled: Acupuncture, Paxlovid (Nirmatrelvir/Ritonavir), N-Acetylcysteine (NAC), Exercise, Hyperbaric Oxygen Therapy (HBOT), Rituximab.
Interactive trial finder
Filter all 629 trials by condition, status, phase, sponsor type and agent, with free-text search and shareable links.
Frequently asked questions
How do I join a clinical trial?
Open the trial's ClinicalTrials.gov record (the "View on ClinicalTrials.gov" button), read the Eligibility Criteria and Contacts and Locations sections, and contact the study team listed there. Trials only enrol at the sites shown in the record, so check whether a site is near you or whether the study is remote/decentralised. Your own clinician can help you judge whether a trial is a sensible option and may need to provide medical records.
Does the Open Source Medicine Foundation run these trials?
No. OSMF does not sponsor, run or recruit for any trial on this page. We compile public registry entries from ClinicalTrials.gov so patients and clinicians can find them in one place. For questions about a specific study, contact the sponsor or study team listed on its ClinicalTrials.gov record.
How often is this list updated?
The underlying dataset is rebuilt automatically from the ClinicalTrials.gov API and these pages are regenerated from it. The date at the top of the page is the last successful refresh. Registry entries can lag the real-world status of a study, so a trial shown as recruiting may already be full.
Why is a trial I know about missing?
Our search targets interventional studies whose registered conditions map to Long COVID / PASC, ME/CFS or overlapping post-viral syndromes. Observational studies, trials registered only on non-US registries (EU CTR, ISRCTN, ANZCTR, etc.), and trials whose condition terms did not match our mapping are not included. The full ClinicalTrials.gov search is always more complete than any curated index.
We summarise newly registered post-viral trials and notable results on the OSMF Substack.
Subscribe on SubstackOpen Source Medicine Foundation. Long COVID, ME/CFS and post-viral clinical trials (629 trials, updated October 2026). Research Tracker, 07 October 2026.
https://research.opensourcemed.info/trials/index.htmlUnderlying dataset (JSON, CC BY 4.0):
https://research.opensourcemed.info/data/clinical_trials/clinical_trials_current.json. Source records: ClinicalTrials.gov.