Executive Summary
Agents by Condition
Top Agents by Linked Trials
Note: Evidence levels are conservative (Strong/Moderate/Preliminary/Anecdotal/Theoretical). Most agents lack large Phase 3 data in these specific populations.
Cross-condition synthesis of therapeutic agents under study for PACVS, Long COVID/PASC, ME/CFS, POTS/Dysautonomia, and MCAS. Data drawn from peer-reviewed literature and registered clinical trials.
Note: Evidence levels are conservative (Strong/Moderate/Preliminary/Anecdotal/Theoretical). Most agents lack large Phase 3 data in these specific populations.
Reusing these data? Please cite the tracker so others can find the source.
Open Source Medicine Foundation. (2026). Therapeutic Agents for Long COVID, PACVS & ME/CFS: Evidence Tracker. Research Tracker. https://research.opensourcemed.info/agents.html (accessed )
New peer-reviewed studies and trial activity across Long COVID, ME/CFS, PACVS, Lyme and Gulf War Illness, every week. Free, no spam.
Subscribe on Substack Browse the digest archive · RSS