Compare conditions

Each comparison page places two conditions side by side: what they are, how many biomarkers OSMF has catalogued and which are shared, how many trials are registered and in what status, which therapeutic agents are under investigation for both, the named research cohorts, and the latest PubMed studies.

Post-infectious and multisymptom conditions

Full biomarker-level comparisons between conditions that have an OSMF biomarker atlas.

Comparison	Shared biomarkers	Direction conflicts	Trials (A / B)	Shared agents
Long COVID vs ME/CFS	18	6	341 / 146	28
Long COVID vs PACVS	5	1	341 / 2	4
Long COVID vs Lyme disease	3	2	341 / 2	4
Long COVID vs Gulf War Illness	10	1	341 / 4	2
ME/CFS vs PACVS	6	2	146 / 2	2
ME/CFS vs Lyme disease	4	2	146 / 2	3
ME/CFS vs Gulf War Illness	13	4	146 / 4	8
PACVS vs Lyme disease	2	0	2 / 2	2
PACVS vs Gulf War Illness	4	0	2 / 4	0
Lyme disease vs Gulf War Illness	4	1	2 / 4	0

Comparisons with POTS and MCAS (literature-only)

POTS and MCAS have no OSMF biomarker atlas, so these pages compare literature, trials, therapeutics and cohorts.

Comparison	Trials (A / B)	Trials listing both	Shared agents
Long COVID vs POTS	341 / 88	12	21
Long COVID vs MCAS	341 / 5	1	3
ME/CFS vs POTS	146 / 88	5	13
ME/CFS vs MCAS	146 / 5	1	2
PACVS vs POTS	2 / 88	0	2
PACVS vs MCAS	2 / 5	0	0
Lyme disease vs POTS	2 / 88	0	3
Lyme disease vs MCAS	2 / 5	0	2
Gulf War Illness vs POTS	4 / 88	0	1
Gulf War Illness vs MCAS	4 / 5	0	0

Conditions covered

Long COVID · biomarker atlas · literature
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) · biomarker atlas · literature
Post-Acute COVID-19 Vaccination Syndrome (PACVS) · biomarker atlas · literature
Lyme Disease · biomarker atlas · literature
Gulf War Illness · biomarker atlas · literature
Postural Orthostatic Tachycardia Syndrome (POTS) · literature
Mast Cell Activation Syndrome (MCAS) · literature

State healthcare law comparison

A separate tool for comparing healthcare-access laws across US states is under development. In the meantime, browse the Medical Freedom Maps layer maps or state profiles.

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Disclaimer. This page is an automated, informational synthesis of public research data maintained by the Open Source Medicine Foundation. It is not medical advice, does not establish a diagnosis, and does not endorse any test or treatment. Biomarker directions summarise individual studies that often disagree; registered trials have not necessarily reported results. Discuss any testing or treatment decision with a qualified clinician.

Last updated 07 Oct 2026. Generated by scripts/build_compare_pages.py.