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Porphobilinogen: biomarker evidence

Porphobilinogen appears in 1 entry of the OSMF biomarker atlas, covering Long COVID. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Long COVID

Where Porphobilinogen is reported

Also listed as: Porphyrin precursor

ConditionDirectionCompared againstAssociated symptomsSource
Long COVID↑ elevatedhealthy controls, recovered individuals without persistent symptomsHeme biosynthesis disruptionSaito et al. 2024

Frequently asked questions

In which conditions is Porphobilinogen altered?

In the OSMF atlas Porphobilinogen is reported in Long COVID. It is elevated in 1 across 1 entries.

Is there a standard clinical test for Porphobilinogen?

The atlas entries for Porphobilinogen do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Porphobilinogen result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Porphobilinogen across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/porphobilinogen.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.