GGT in NAFLD / MASH (Metabolic-Associated Steatohepatitis)

GGT belongs to the hepatic group of NAFLD / MASH (Metabolic-Associated Steatohepatitis) markers and is reported to be raised relative to the reference group of the cited comparison (NAFLD with elevated inflammatory activity vs lower GGT levels). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. The finding is drawn from Liang et al. 2023; it describes group-level differences, not a threshold that classifies an individual.

↑ ElevatedHepatic

Summary

Direction in NAFLD / MASH (Metabolic-Associated Steatohepatitis)↑ Elevated — higher than in the comparison group
CategoryHepatic
Compared againstNAFLD with elevated inflammatory activity vs lower GGT levels
SourceLiang et al. 2023 — doi:10.1016/j.jhep.2023.04.025
Condition atlasNAFLD / MASH (Metabolic-Associated Steatohepatitis) Biomarker Atlas

Related Hepatic markers in NAFLD / MASH (Metabolic-Associated Steatohepatitis)

Full list: NAFLD / MASH (Metabolic-Associated Steatohepatitis) Biomarker Atlas.

Frequently asked questions

Is GGT high or low in NAFLD / MASH (Metabolic-Associated Steatohepatitis)?

Elevated. Studies summarised in the OSMF atlas report higher GGT in NAFLD / MASH (Metabolic-Associated Steatohepatitis) than in the reference group of the cited comparison (NAFLD with elevated inflammatory activity vs lower GGT levels). Source: Liang et al. 2023.

Which test measures GGT?

The atlas record does not list a standardised clinical test code (LOINC) for GGT, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal GGT result diagnostic of NAFLD / MASH (Metabolic-Associated Steatohepatitis)?

No. No single biomarker is diagnostic of NAFLD / MASH (Metabolic-Associated Steatohepatitis). GGT findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). GGT in NAFLD / MASH (Metabolic-Associated Steatohepatitis): direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/nafld-mash-metabolic-associated-steatohepatitis/ggt.html
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Last reviewed: 2026-07-03 · Page generated from nafld-mash-metabolic-associated-steatohepatitis.json · Browse: NAFLD / MASH (Metabolic-Associated Steatohepatitis) atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.