D-dimer across conditions

D-dimer appears in 2 entries of the OSMF biomarker atlas, covering Atrial Fibrillation, Long COVID. Across those entries it is elevated in 2. Because the same marker shifts in several unrelated conditions, it is best understood as a signal of shared biology such as inflammation, vascular or metabolic stress rather than as a condition-specific test. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Atrial FibrillationLong COVID

Where D-dimer is reported

Also listed as: Fibrin degradation product

ConditionDirectionCompared againstAssociated symptomsSource
Atrial Fibrillation↑ elevatedAF vs healthy/non-AF—Rafaqat et al. 2024
Long COVID↑ elevatedhealthy controls, recovered individuals without persistent symptomsCoagulopathy, thrombotic riskLai et al. 2023; Thomas et al. 2024

Frequently asked questions

In which conditions is D-dimer altered?

In the OSMF atlas D-dimer is reported in Atrial Fibrillation, Long COVID. It is elevated in 2 across 2 entries.

Does D-dimer point to one specific diagnosis?

No. Because D-dimer changes in several conditions (Atrial Fibrillation, Long COVID), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.

What is the LOINC code for D-dimer?

Entries in this atlas use LOINC 48065-7. LOINC codes identify the laboratory observation so results can be compared across systems.

Is one abnormal D-dimer result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). D-dimer across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/d-dimer.html
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.