Summary
| Direction in PACVS | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Metabolic |
| Also described as | Anaerobic threshold marker |
| Compared against | HC (healthy controls) |
| Associated symptoms | Earlier lactate threshold, PEM |
| Test type | Blood test (serum / plasma / whole blood) |
| Source | Halma & Varon 2025 — doi:10.1016/j.biopha.2025.118864 |
| Condition atlas | PACVS Biomarker Atlas |
Trials, interventions and tests
In clinical-trial registrations this marker maps to the outcome term Sedentary blood lactate (1 registered trials use a matching outcome measure).
Clinical trials using Blood lactate (exercise) as an outcome
- NCT06967428: Effect of Metabolic Modulation on a Post-acute COVID-19 Vaccination Syndrome (PACVS) Cohort (Not Yet Recruiting)
Outcome measure: Sedentary blood lactate
Related Metabolic markers in PACVS
Full list: PACVS Biomarker Atlas.
Frequently asked questions
Is Blood lactate (exercise) high or low in PACVS?
Elevated. Studies summarised in the OSMF atlas report higher Blood lactate (exercise) in PACVS than in healthy controls. Source: Halma & Varon 2025.
What symptoms is Blood lactate (exercise) associated with in PACVS?
The cited literature associates this marker with Earlier lactate threshold, PEM. These are population-level associations and do not mean the marker causes the symptoms.
Which test measures Blood lactate (exercise)?
It is measured as a blood test (serum / plasma / whole blood). Many of the cited studies used research-grade assays, so clinical availability may vary.
Is one abnormal Blood lactate (exercise) result diagnostic of PACVS?
No. No single biomarker is diagnostic of PACVS. Blood lactate (exercise) findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-06-30 · Page generated from pacvs.json · Browse: PACVS atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.