Ferritin index in PACVS

Ferritin index, also described as Iron metabolism marker, is a metabolic marker reported as reduced in PACVS (PACVS, PCVS) when patients are compared with healthy controls. The cited literature links this alteration to impaired iron storage in >50% of PACVS subjects. The evidence summarised here comes from Mundorf et al. 2024 and reflects averages across cohorts rather than any single patient's result.

↓ ReducedMetabolicLOINC 2276-4

Summary

Direction in PACVS↓ Reduced — lower than in the comparison group
CategoryMetabolic
Also described asIron metabolism marker
Compared againstHC (healthy controls)
Associated symptomsImpaired iron storage in >50% of PACVS subjects
Test typeBlood test (serum / plasma / whole blood)
LOINC code2276-4
SourceMundorf et al. 2024 — doi:10.3390/vaccines12070790
Condition atlasPACVS Biomarker Atlas

Other conditions where Ferritin is reported

See the cross-condition hub: Ferritin across conditions.

Trials, interventions and tests

Commercial test availability

Ferritin — commercial laboratory test.

Links are for reference only; availability, specimen requirements and coverage vary by location.

Related Metabolic markers in PACVS

Full list: PACVS Biomarker Atlas.

Frequently asked questions

Is Ferritin index high or low in PACVS?

Reduced. Studies summarised in the OSMF atlas report lower Ferritin index in PACVS than in healthy controls. Source: Mundorf et al. 2024.

What symptoms is Ferritin index associated with in PACVS?

The cited literature associates this marker with Impaired iron storage in >50% of PACVS subjects. These are population-level associations and do not mean the marker causes the symptoms.

Which test measures Ferritin index?

It is measured as a blood test (serum / plasma / whole blood). The standard laboratory code is LOINC 2276-4. Commercial laboratories such as Quest Diagnostics, LabCorp, Ulta Lab Tests list an orderable assay.

Is one abnormal Ferritin index result diagnostic of PACVS?

No. No single biomarker is diagnostic of PACVS. Ferritin index findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Is Ferritin index specific to PACVS?

No. The same marker is also reported in Long COVID, NAFLD / MASH (Metabolic-Associated Steatohepatitis) in this atlas, so it reflects shared biology (for example inflammation or vascular stress) rather than a condition-specific signature.

Cite this page

Open Source Medicine Foundation. (2026). Ferritin index in PACVS: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/pacvs/ferritin-index.html
Get OSMF research updates. New biomarker, trial and treatment evidence summaries by email.
Subscribe on Substack

Last reviewed: 2026-06-30 · Page generated from pacvs.json · Browse: PACVS atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.