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Ferritin across conditions

Ferritin appears in 3 entries of the OSMF biomarker atlas, covering Long COVID, NAFLD / MASH (Metabolic-Associated Steatohepatitis), PACVS. Across those entries it is elevated in 1, reduced in 1, mixed in 1. Because the same marker shifts in several unrelated conditions, it is best understood as a signal of shared biology such as inflammation, vascular or metabolic stress rather than as a condition-specific test. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Long COVIDNAFLD / MASH (Metabolic-Associated Steatohepatitis)PACVS

Where Ferritin is reported

Also listed as: Acute phase reactant; Ferritin index; Iron metabolism marker

ConditionDirectionCompared againstAssociated symptomsSource
Long COVID↕ inconsistenthealthy controlsIron metabolism dysregulationThomas et al. 2024
NAFLD / MASH (Metabolic-Associated Steatohepatitis)↑ elevatedNAFLD vs normal/no iron overload—Padureanu et al. 2021
PACVS↓ reducedhealthy controlsImpaired iron storage in >50% of PACVS subjectsMundorf et al. 2024

Frequently asked questions

In which conditions is Ferritin altered?

In the OSMF atlas Ferritin is reported in Long COVID, NAFLD / MASH (Metabolic-Associated Steatohepatitis), PACVS. It is elevated in 1, reduced in 1, mixed in 1 across 3 entries.

Does Ferritin point to one specific diagnosis?

No. Because Ferritin changes in several conditions (Long COVID, NAFLD / MASH (Metabolic-Associated Steatohepatitis), PACVS), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.

What is the LOINC code for Ferritin?

Entries in this atlas use LOINC 2276-4. LOINC codes identify the laboratory observation so results can be compared across systems.

Is one abnormal Ferritin result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Ferritin across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/ferritin.html
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.