Summary
| Direction in Alzheimer's Disease and Other Dementias | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Neurological |
| Compared against | PSEN1 E280A mutation non-carriers |
| Associated symptoms | not specified |
| Source | Malotaux et al. 2025 — doi:10.1002/alz.70421 |
| Condition atlas | Alzheimer's Disease and Other Dementias Biomarker Atlas |
Related Neurological markers in Alzheimer's Disease and Other Dementias
Full list: Alzheimer's Disease and Other Dementias Biomarker Atlas.
Frequently asked questions
Is Plasma p-tau217 high or low in Alzheimer's Disease and Other Dementias?
Elevated. Studies summarised in the OSMF atlas report higher Plasma p-tau217 in Alzheimer's Disease and Other Dementias than in PSEN1 E280A mutation non-carriers. Source: Malotaux et al. 2025.
What symptoms is Plasma p-tau217 associated with in Alzheimer's Disease and Other Dementias?
The cited literature associates this marker with not specified. These are population-level associations and do not mean the marker causes the symptoms.
Which test measures Plasma p-tau217?
The atlas record does not list a standardised clinical test code (LOINC) for Plasma p-tau217, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.
Is one abnormal Plasma p-tau217 result diagnostic of Alzheimer's Disease and Other Dementias?
No. No single biomarker is diagnostic of Alzheimer's Disease and Other Dementias. Plasma p-tau217 findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-10-08 · Page generated from alzheimer-s-disease-and-other-dementias.json · Browse: Alzheimer's Disease and Other Dementias atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.