Total Tau in Alzheimer's Disease and Other Dementias

Elevated. Studies summarised in the OSMF atlas report higher Total Tau in Alzheimer's Disease and Other Dementias than in the reference group of the cited comparison (AD vs healthy/non-AD (core CSF/plasma biomarker)). Source: Abukuri et al. 2024.

The atlas record does not list a standardised clinical test code (LOINC) for Total Tau, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

No. No single biomarker is diagnostic of Alzheimer's Disease and Other Dementias. Total Tau findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.