Resistin in Long COVID

In Long COVID (PASC, Post-Acute Sequelae of COVID-19), published studies report higher levels of Resistin, also described as Adipokine, than in healthy controls. Symptom domains tied to this marker in the source include insulin resistance, inflammation. The evidence summarised here comes from Lai et al. 2023 and reflects averages across cohorts rather than any single patient's result.

↑ ElevatedVascularLOINC 42702-4

Summary

Direction in Long COVID↑ Elevated — higher than in the comparison group
CategoryVascular
Also described asAdipokine
Compared againstHC (healthy controls)
Associated symptomsInsulin resistance, inflammation
Test typeBlood test (serum / plasma / whole blood)
LOINC code42702-4
SourceLai et al. 2023 — doi:10.3389/fmed.2023.1085988
Condition atlasLong COVID Biomarker Atlas

Other conditions where Resistin is reported

See the cross-condition hub: Resistin across conditions.

Trials, interventions and tests

Commercial test availability

Resistin — specialty laboratory test. Limited commercial availability; often research use.

Links are for reference only; availability, specimen requirements and coverage vary by location.

Related Vascular markers in Long COVID

Full list: Long COVID Biomarker Atlas.

Frequently asked questions

Is Resistin high or low in Long COVID?

Elevated. Studies summarised in the OSMF atlas report higher Resistin in Long COVID than in healthy controls. Source: Lai et al. 2023.

What symptoms is Resistin associated with in Long COVID?

The cited literature associates this marker with Insulin resistance, inflammation. These are population-level associations and do not mean the marker causes the symptoms.

Which test measures Resistin?

It is measured as a blood test (serum / plasma / whole blood). The standard laboratory code is LOINC 42702-4. Commercial laboratories such as ARUP Laboratories list an orderable assay.

Is one abnormal Resistin result diagnostic of Long COVID?

No. No single biomarker is diagnostic of Long COVID. Resistin findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Is Resistin specific to Long COVID?

No. The same marker is also reported in ME/CFS in this atlas, so it reflects shared biology (for example inflammation or vascular stress) rather than a condition-specific signature.

Cite this page

Open Source Medicine Foundation. (2026). Resistin in Long COVID: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/long-covid/resistin.html
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Last reviewed: 2026-06-29 · Page generated from long-covid.json · Browse: Long COVID atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.