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2-day CPET VO₂ peak (day 2): biomarker evidence

2-day CPET VO₂ peak (day 2) appears in 1 entry of the OSMF biomarker atlas, covering ME/CFS. Across those entries it is reduced in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

ME/CFS

Where 2-day CPET VO₂ peak (day 2) is reported

Also listed as: Cardiopulmonary exercise test

ConditionDirectionCompared againstAssociated symptomsSource
ME/CFS↓ reducedDay 1 vs Day 2PEM, exercise intoleranceHolden et al. 2020

Frequently asked questions

In which conditions is 2-day CPET VO₂ peak (day 2) altered?

In the OSMF atlas 2-day CPET VO₂ peak (day 2) is reported in ME/CFS. It is reduced in 1 across 1 entries.

Is there a standard clinical test for 2-day CPET VO₂ peak (day 2)?

The atlas entries for 2-day CPET VO₂ peak (day 2) do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal 2-day CPET VO₂ peak (day 2) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). 2-day CPET VO₂ peak (day 2) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/2-day-cpet-vo2-peak-day-2.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.