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Phosphorylated Tau (p-tau181): biomarker evidence

Phosphorylated Tau (p-tau181) appears in 1 entry of the OSMF biomarker atlas, covering Alzheimer's Disease and Other Dementias. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Alzheimer's Disease and Other Dementias

Where Phosphorylated Tau (p-tau181) is reported

ConditionDirectionCompared againstAssociated symptomsSource
Alzheimer's Disease and Other Dementias↑ elevatedAD vs healthy/non-AD (core CSF/plasma biomarker)—Abukuri et al. 2024

Frequently asked questions

In which conditions is Phosphorylated Tau (p-tau181) altered?

In the OSMF atlas Phosphorylated Tau (p-tau181) is reported in Alzheimer's Disease and Other Dementias. It is elevated in 1 across 1 entries.

Is there a standard clinical test for Phosphorylated Tau (p-tau181)?

The atlas entries for Phosphorylated Tau (p-tau181) do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Phosphorylated Tau (p-tau181) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Phosphorylated Tau (p-tau181) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/phosphorylated-tau-p-tau181.html
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.