Serum Magnesium in Migraine

In Migraine, published studies report lower levels of Serum Magnesium than in the reference group of the cited comparison (adolescents (age subgroup) with migraine vs age/sex-matched controls without headache). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. The finding is drawn from Bhurat et al. 2022; it describes group-level differences, not a threshold that classifies an individual.

↓ ReducedNeurological

Summary

Direction in Migraine↓ Reduced — lower than in the comparison group
CategoryNeurological
Compared againstadolescents (age subgroup) with migraine vs age/sex-matched controls without headache
SourceBhurat et al. 2022 — doi:10.1007/s13312-022-2576-4
Condition atlasMigraine Biomarker Atlas

Related Neurological markers in Migraine

Full list: Migraine Biomarker Atlas.

Frequently asked questions

Is Serum Magnesium high or low in Migraine?

Reduced. Studies summarised in the OSMF atlas report lower Serum Magnesium in Migraine than in the reference group of the cited comparison (adolescents (age subgroup) with migraine vs age/sex-matched controls without headache). Source: Bhurat et al. 2022.

Which test measures Serum Magnesium?

The atlas record does not list a standardised clinical test code (LOINC) for Serum Magnesium, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal Serum Magnesium result diagnostic of Migraine?

No. No single biomarker is diagnostic of Migraine. Serum Magnesium findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). Serum Magnesium in Migraine: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/migraine/serum-magnesium.html
Get OSMF research updates. New biomarker, trial and treatment evidence summaries by email.
Subscribe on Substack

Last reviewed: 2026-07-03 · Page generated from migraine.json · Browse: Migraine atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.