Research Tracker›Biomarker Atlas›COPD›Fibrinogen

Fibrinogen in COPD

Fibrinogen belongs to the inflammatory group of COPD markers and is reported to be raised relative to the reference group of the cited comparison (smokers/COPD vs non-smokers). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. The evidence summarised here comes from Yanbaeva et al. 2007 and reflects averages across cohorts rather than any single patient's result.

↑ ElevatedInflammatoryLOINC 3255-7

Summary

Direction in COPD↑ Elevated — higher than in the comparison group
CategoryInflammatory
Compared againstsmokers/COPD vs non-smokers
Test typeBlood test (serum / plasma / whole blood)
LOINC code3255-7
SourceYanbaeva et al. 2007 — doi:10.1378/chest.06-2179
Condition atlasCOPD Biomarker Atlas

Other conditions where Fibrinogen is reported

See the cross-condition hub: Fibrinogen across conditions.

Related Inflammatory markers in COPD

Full list: COPD Biomarker Atlas.

Frequently asked questions

Is Fibrinogen high or low in COPD?

Elevated. Studies summarised in the OSMF atlas report higher Fibrinogen in COPD than in the reference group of the cited comparison (smokers/COPD vs non-smokers). Source: Yanbaeva et al. 2007.

Which test measures Fibrinogen?

It is measured as a blood test (serum / plasma / whole blood). The standard laboratory code is LOINC 3255-7. Many of the cited studies used research-grade assays, so clinical availability may vary.

Is one abnormal Fibrinogen result diagnostic of COPD?

No. No single biomarker is diagnostic of COPD. Fibrinogen findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Is Fibrinogen specific to COPD?

No. The same marker is also reported in Long COVID in this atlas, so it reflects shared biology (for example inflammation or vascular stress) rather than a condition-specific signature.

Cite this page

Open Source Medicine Foundation. (2026). Fibrinogen in COPD: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/copd/fibrinogen.html
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Last reviewed: 2026-07-03 · Page generated from copd.json · Browse: COPD atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.