CSF CXCL13: biomarker evidence

CSF CXCL13 appears in 1 entry of the OSMF biomarker atlas, covering Lyme Disease. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Lyme Disease

Where CSF CXCL13 is reported

Also listed as: B-cell chemoattractant

ConditionDirectionCompared againstAssociated symptomsSource
Lyme Disease↑ elevatedNon-neuroborreliosis controlsNeuroborreliosis — high specificityRupprecht et al. 2005

Frequently asked questions

In which conditions is CSF CXCL13 altered?

In the OSMF atlas CSF CXCL13 is reported in Lyme Disease. It is elevated in 1 across 1 entries.

Is there a standard clinical test for CSF CXCL13?

The atlas entries for CSF CXCL13 do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal CSF CXCL13 result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). CSF CXCL13 across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/csf-cxcl13.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.