Where CD8+ T cell perforin is reported
Also listed as: Cytotoxic effector molecule
| Condition | Direction | Compared against | Associated symptoms | Source |
|---|---|---|---|---|
| ME/CFS | ↓ reduced | healthy controls | T cell dysfunction | Maksoud et al. 2023 |
Frequently asked questions
In which conditions is CD8+ T cell perforin altered?
In the OSMF atlas CD8+ T cell perforin is reported in ME/CFS. It is reduced in 1 across 1 entries.
Is there a standard clinical test for CD8+ T cell perforin?
The atlas entries for CD8+ T cell perforin do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.
Is one abnormal CD8+ T cell perforin result diagnostic?
No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas
Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.