Salivary Pepsin in GERD (Gastroesophageal Reflux Disease)

Elevated. Studies summarised in the OSMF atlas report higher Salivary Pepsin in GERD (Gastroesophageal Reflux Disease) than in the reference group of the cited comparison (GERD/hypersensitive esophagus patients vs asymptomatic healthy controls). Source: Hayat et al. 2015.

The atlas record does not list a standardised clinical test code (LOINC) for Salivary Pepsin, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

No. No single biomarker is diagnostic of GERD (Gastroesophageal Reflux Disease). Salivary Pepsin findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.