Summary
| Direction in GERD (Gastroesophageal Reflux Disease) | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Gastrointestinal |
| Also described as | Acid Exposure Time |
| Compared against | GERD patients (by MII-pH monitoring) vs asymptomatic healthy controls/functional heartburn |
| Source | Hayat et al. 2015 — doi:10.1136/gutjnl-2014-307049 |
| Condition atlas | GERD (Gastroesophageal Reflux Disease) Biomarker Atlas |
Related Gastrointestinal markers in GERD (Gastroesophageal Reflux Disease)
Full list: GERD (Gastroesophageal Reflux Disease) Biomarker Atlas.
Frequently asked questions
Is Esophageal Acid Exposure Time high or low in GERD (Gastroesophageal Reflux Disease)?
Elevated. Studies summarised in the OSMF atlas report higher Esophageal Acid Exposure Time in GERD (Gastroesophageal Reflux Disease) than in the reference group of the cited comparison (GERD patients (by MII-pH monitoring) vs asymptomatic healthy controls/functional heartburn). Source: Hayat et al. 2015.
Which test measures Esophageal Acid Exposure Time?
The atlas record does not list a standardised clinical test code (LOINC) for Esophageal Acid Exposure Time, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.
Is one abnormal Esophageal Acid Exposure Time result diagnostic of GERD (Gastroesophageal Reflux Disease)?
No. No single biomarker is diagnostic of GERD (Gastroesophageal Reflux Disease). Esophageal Acid Exposure Time findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-07-03 · Page generated from gerd-gastroesophageal-reflux-disease.json · Browse: GERD (Gastroesophageal Reflux Disease) atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.