Peer-Reviewed Literature Synthesis

Epilepsy Biomarker Atlas

Molecular alterations reported in Epilepsy compared to healthy controls, from peer-reviewed literature.

Spontaneous remission60-85% achieve seizure freedom on medication; of those, 50-75% remain seizure-free after withdrawal (varies by…
Best-intervention remissionNot clearly higher than on-medication rates -- the real gap is behavioral/practice
Gap sizeSmall biological gap; large practice gap
Primary barrierpractice
Full remission profile →

Literature Overview

Biomarkers below are included only where peer-reviewed literature explicitly reports the marker's direction in Epilepsy patients relative to a named comparison population — not inferred.

3
Curated markers
1
Categories

Searchable Alterations Database

Comparison populations are quoted as reported in the source literature (e.g. healthy controls, disease-matched patients).

Marker / TestDirectionCategoryvs. ComparisonClinical ContextKey Reference

Key References

Peer-Reviewed Literature

Hanin et al. 2022

DOI: 10.1007/s00415-022-11004-2 →
Peer-Reviewed Literature

Bauer 1996

DOI: 10.1016/0920-1211(96)00009-5 →
Peer-Reviewed Literature

Simani et al. 2020

DOI: 10.1021/acschemneuro.0c00492 →
Disclaimer: Educational synthesis of peer-reviewed literature only — not medical advice. Markers are drawn from published disease-vs-comparison-population studies; inclusion here does not imply diagnostic or clinical validation. Consult a qualified healthcare professional for interpretation.

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