Research Tracker›Biomarker Atlas›Inflammatory Bowel Disease (Crohn's/UC)›Fecal Calprotectin

Fecal Calprotectin in Inflammatory Bowel Disease (Crohn's/UC)

Fecal Calprotectin belongs to the immune group of Inflammatory Bowel Disease (Crohn's/UC) markers and is reported to be raised relative to the reference group of the cited comparison (IBD patients vs non-IBD/healthy). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. This entry summarises Tibble et al. 2001. Group-level associations like this do not translate into an individual diagnostic cut-off.

↑ ElevatedImmune

Summary

Direction in Inflammatory Bowel Disease (Crohn's/UC)↑ Elevated — higher than in the comparison group
CategoryImmune
Compared againstIBD patients vs non-IBD/healthy
SourceTibble et al. 2001 — doi:10.3748/wjg.v7.i4.460
Condition atlasInflammatory Bowel Disease (Crohn's/UC) Biomarker Atlas

Related Immune markers in Inflammatory Bowel Disease (Crohn's/UC)

Full list: Inflammatory Bowel Disease (Crohn's/UC) Biomarker Atlas.

Frequently asked questions

Is Fecal Calprotectin high or low in Inflammatory Bowel Disease (Crohn's/UC)?

Elevated. Studies summarised in the OSMF atlas report higher Fecal Calprotectin in Inflammatory Bowel Disease (Crohn's/UC) than in the reference group of the cited comparison (IBD patients vs non-IBD/healthy). Source: Tibble et al. 2001.

Which test measures Fecal Calprotectin?

The atlas record does not list a standardised clinical test code (LOINC) for Fecal Calprotectin, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal Fecal Calprotectin result diagnostic of Inflammatory Bowel Disease (Crohn's/UC)?

No. No single biomarker is diagnostic of Inflammatory Bowel Disease (Crohn's/UC). Fecal Calprotectin findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). Fecal Calprotectin in Inflammatory Bowel Disease (Crohn's/UC): direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/inflammatory-bowel-disease-crohn-s-uc/fecal-calprotectin.html
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Last reviewed: 2026-07-03 · Page generated from inflammatory-bowel-disease-crohn-s-uc.json · Browse: Inflammatory Bowel Disease (Crohn's/UC) atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.