ASCA Antibodies in Inflammatory Bowel Disease (Crohn's/UC)

ASCA Antibodies, also described as ASCA, is a immune marker reported as elevated in Inflammatory Bowel Disease (Crohn's/UC) when patients are compared with the reference group of the cited comparison (Crohn's disease patients vs ulcerative colitis patients and controls). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. This entry summarises Zholudev et al. 2004. Group-level associations like this do not translate into an individual diagnostic cut-off.

↑ ElevatedImmune

Summary

Direction in Inflammatory Bowel Disease (Crohn's/UC)↑ Elevated — higher than in the comparison group
CategoryImmune
Also described asASCA
Compared againstCrohn's disease patients vs ulcerative colitis patients and controls
SourceZholudev et al. 2004 — doi:10.1111/j.1572-0241.2004.40369.x
Condition atlasInflammatory Bowel Disease (Crohn's/UC) Biomarker Atlas

Related Immune markers in Inflammatory Bowel Disease (Crohn's/UC)

Full list: Inflammatory Bowel Disease (Crohn's/UC) Biomarker Atlas.

Frequently asked questions

Is ASCA Antibodies high or low in Inflammatory Bowel Disease (Crohn's/UC)?

Elevated. Studies summarised in the OSMF atlas report higher ASCA Antibodies in Inflammatory Bowel Disease (Crohn's/UC) than in the reference group of the cited comparison (Crohn's disease patients vs ulcerative colitis patients and controls). Source: Zholudev et al. 2004.

Which test measures ASCA Antibodies?

The atlas record does not list a standardised clinical test code (LOINC) for ASCA Antibodies, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal ASCA Antibodies result diagnostic of Inflammatory Bowel Disease (Crohn's/UC)?

No. No single biomarker is diagnostic of Inflammatory Bowel Disease (Crohn's/UC). ASCA Antibodies findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). ASCA Antibodies in Inflammatory Bowel Disease (Crohn's/UC): direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/inflammatory-bowel-disease-crohn-s-uc/asca-antibodies.html
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Last reviewed: 2026-07-03 · Page generated from inflammatory-bowel-disease-crohn-s-uc.json · Browse: Inflammatory Bowel Disease (Crohn's/UC) atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.