{
  "slug": "inflammatory-bowel-disease-crohn-s-uc",
  "id": "inflammatory-bowel-disease-crohn-s-uc-biomarkers",
  "condition": {
    "name": "Inflammatory Bowel Disease (Crohn's/UC)",
    "shortName": "Inflammatory Bowel Disease (Crohn's/UC)",
    "alternateNames": []
  },
  "page": {
    "title": "Inflammatory Bowel Disease (Crohn's/UC) Biomarker Atlas | Blood Tests & Molecular Alterations",
    "breadcrumbName": "Inflammatory Bowel Disease (Crohn's/UC) Biomarkers",
    "description": "Searchable atlas of Inflammatory Bowel Disease (Crohn's/UC) biomarkers, from peer-reviewed literature comparing patient levels vs. healthy controls.",
    "keywords": [
      "Inflammatory Bowel Disease (Crohn's/UC) biomarkers",
      "Inflammatory Bowel Disease (Crohn's/UC) blood tests",
      "biomarker atlas",
      "biomarker database"
    ],
    "canonical": "https://research.opensourcemed.info/inflammatory-bowel-disease-crohn-s-uc-biomarkers.html",
    "hero": "Molecular alterations reported in Inflammatory Bowel Disease (Crohn's/UC) compared to healthy controls, from peer-reviewed literature.",
    "dateModified": "2026-07-03"
  },
  "categories": {
    "immune": "Immune",
    "inflammatory": "Inflammatory"
  },
  "filters": [
    "immune",
    "inflammatory"
  ],
  "markers": [
    {
      "name": "ANCA Antibodies",
      "alternateName": "ANCA",
      "direction": "up",
      "category": "immune",
      "comparison": "ulcerative colitis patients vs non-UC controls and healthy controls",
      "symptoms": "",
      "reference": {
        "citation": "Pang et al. 2020",
        "doi": "10.1186/s13223-020-00433-1"
      }
    },
    {
      "name": "ASCA Antibodies",
      "alternateName": "ASCA",
      "direction": "up",
      "category": "immune",
      "comparison": "Crohn's disease patients vs ulcerative colitis patients and controls",
      "symptoms": "",
      "reference": {
        "citation": "Zholudev et al. 2004",
        "doi": "10.1111/j.1572-0241.2004.40369.x"
      }
    },
    {
      "name": "CRP",
      "alternateName": "CRP",
      "direction": "up",
      "category": "inflammatory",
      "comparison": "active/moderate-to-severe IBD vs symptomatic remission",
      "symptoms": "",
      "reference": {
        "citation": "Singh et al. 2023",
        "doi": "10.1053/j.gastro.2022.12.007"
      },
      "testType": "BloodTest",
      "loinc": "1988-5"
    },
    {
      "name": "ESR",
      "alternateName": "ESR",
      "direction": "up",
      "category": "inflammatory",
      "comparison": "active IBD vs quiescent/baseline disease",
      "symptoms": "",
      "reference": {
        "citation": "Ondrej\u010d\u00e1kov\u00e1 et al. 2024",
        "doi": "10.1016/j.autrev.2023.103512"
      }
    },
    {
      "name": "Fecal Calprotectin",
      "alternateName": "Fecal Calprotectin",
      "direction": "up",
      "category": "immune",
      "comparison": "IBD patients vs non-IBD/healthy",
      "symptoms": "",
      "reference": {
        "citation": "Tibble et al. 2001",
        "doi": "10.3748/wjg.v7.i4.460"
      }
    }
  ]
}