Peer-Reviewed Literature Synthesis

Asthma Biomarker Atlas

Molecular alterations reported in Asthma compared to healthy controls, from peer-reviewed literature.

Spontaneous remission26% of childhood-onset asthma in clinical remission by adulthood; <20% adult-onset achieves sustained remission; 65%…
Best-intervention remissionBiologics (anti-IL-5, anti-IL-4/13, anti-IgE) achieve near-zero exacerbation rates in eligible severe patients…
Gap sizeModerate; highly severity-dependent; large practice gap for AIT
Primary barrierbiological (severe phenotype) + practice (AIT underutilized)
Full remission profile →

Literature Overview

Biomarkers below are included only where peer-reviewed literature explicitly reports the marker's direction in Asthma patients relative to a named comparison population — not inferred.

4
Curated markers
1
Categories

Searchable Alterations Database

Comparison populations are quoted as reported in the source literature (e.g. healthy controls, disease-matched patients).

Marker / TestDirectionCategoryvs. ComparisonClinical ContextKey Reference

Key References

Peer-Reviewed Literature

Bacharier et al. 2024

DOI: 10.1016/j.jaci.2023.09.044 →
Peer-Reviewed Literature

Loewenthal et al. 2022

DOI: 10.1055/s-0042-1743290 →
Peer-Reviewed Literature

Sonnenberg-Riethmacher et al. 2021

DOI: 10.3389/fimmu.2021.722170 →
Peer-Reviewed Literature

Schatz et al. 2014

DOI: 10.1016/j.jaip.2014.09.004 →
Disclaimer: Educational synthesis of peer-reviewed literature only — not medical advice. Markers are drawn from published disease-vs-comparison-population studies; inclusion here does not imply diagnostic or clinical validation. Consult a qualified healthcare professional for interpretation.

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