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Total IgE in Asthma

Total IgE belongs to the pulmonary group of Asthma markers and is reported to be raised relative to the reference group of the cited comparison (allergic asthma vs non-allergic asthma). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. The evidence summarised here comes from Schatz et al. 2014 and reflects averages across cohorts rather than any single patient's result.

↑ ElevatedPulmonary

Summary

Direction in Asthma↑ Elevated — higher than in the comparison group
CategoryPulmonary
Compared againstallergic asthma vs non-allergic asthma
SourceSchatz et al. 2014 — doi:10.1016/j.jaip.2014.09.004
Condition atlasAsthma Biomarker Atlas

Related Pulmonary markers in Asthma

Full list: Asthma Biomarker Atlas.

Frequently asked questions

Is Total IgE high or low in Asthma?

Elevated. Studies summarised in the OSMF atlas report higher Total IgE in Asthma than in the reference group of the cited comparison (allergic asthma vs non-allergic asthma). Source: Schatz et al. 2014.

Which test measures Total IgE?

The atlas record does not list a standardised clinical test code (LOINC) for Total IgE, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal Total IgE result diagnostic of Asthma?

No. No single biomarker is diagnostic of Asthma. Total IgE findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). Total IgE in Asthma: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/asthma/total-ige.html
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Last reviewed: 2026-07-02 · Page generated from asthma.json · Browse: Asthma atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.