Research Tracker›Biomarker Atlas›Marker Pages›RNase L (37-kDa fragment)

RNase L (37-kDa fragment): biomarker evidence

RNase L (37-kDa fragment) appears in 1 entry of the OSMF biomarker atlas, covering ME/CFS. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

ME/CFS

Where RNase L (37-kDa fragment) is reported

Also listed as: Antiviral pathway enzyme

ConditionDirectionCompared againstAssociated symptomsSource
ME/CFS↑ elevatedhealthy controlsChronic immune activationMaksoud et al. 2023

Frequently asked questions

In which conditions is RNase L (37-kDa fragment) altered?

In the OSMF atlas RNase L (37-kDa fragment) is reported in ME/CFS. It is elevated in 1 across 1 entries.

Is there a standard clinical test for RNase L (37-kDa fragment)?

The atlas entries for RNase L (37-kDa fragment) do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal RNase L (37-kDa fragment) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). RNase L (37-kDa fragment) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/rnase-l-37-kda-fragment.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.