Summary
| Direction in Multiple Sclerosis | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Other |
| Compared against | healthy controls |
| Source | Brown et al. 2012 — doi:10.2478/s13380-012-0028-7 |
| Condition atlas | Multiple Sclerosis Biomarker Atlas |
Related Other markers in Multiple Sclerosis
Full list: Multiple Sclerosis Biomarker Atlas.
Frequently asked questions
Is Osteopontin high or low in Multiple Sclerosis?
Elevated. Studies summarised in the OSMF atlas report higher Osteopontin in Multiple Sclerosis than in healthy controls. Source: Brown et al. 2012.
Which test measures Osteopontin?
The atlas record does not list a standardised clinical test code (LOINC) for Osteopontin, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.
Is one abnormal Osteopontin result diagnostic of Multiple Sclerosis?
No. No single biomarker is diagnostic of Multiple Sclerosis. Osteopontin findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-10-08 · Page generated from multiple-sclerosis.json · Browse: Multiple Sclerosis atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.