CSF Kappa Free Light Chains in Multiple Sclerosis

Elevated. Studies summarised in the OSMF atlas report higher CSF Kappa Free Light Chains in Multiple Sclerosis than in patients with other neurological inflammatory disorders and non-inflammatory diseases. Source: Vecchio et al. 2024.

The atlas record does not list a standardised clinical test code (LOINC) for CSF Kappa Free Light Chains, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

No. No single biomarker is diagnostic of Multiple Sclerosis. CSF Kappa Free Light Chains findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.