Peer-Reviewed Literature Synthesis

Type 1 Diabetes Biomarker Atlas

Molecular alterations reported in Type 1 Diabetes compared to healthy controls, from peer-reviewed literature.

Spontaneous remissionEssentially zero for established T1DM (honeymoon phase occurs in 50-60% after diagnosis but lasts 3-12 months then…
Best-intervention remissionClosed-loop insulin delivery (artificial pancreas systems — Control-IQ, Omnipod 5) achieves 70-80% time-in-range vs…
Gap sizeModerate-large — closed-loop approaches are increasingly standard but true insulin independence is rare with any…
Primary barrierbiological + access
Full remission profile →

Literature Overview

Biomarkers below are included only where peer-reviewed literature explicitly reports the marker's direction in Type 1 Diabetes patients relative to a named comparison population — not inferred.

6
Curated markers
1
Categories

Searchable Alterations Database

Comparison populations are quoted as reported in the source literature (e.g. healthy controls, disease-matched patients).

Marker / TestDirectionCategoryvs. ComparisonClinical ContextKey Reference

Key References

Peer-Reviewed Literature

Yu et al. 2019

DOI: 10.1172/JCI127397 →
Peer-Reviewed Literature

Yang et al. 2024

DOI: 10.1136/bmj-2023-078432 →
Peer-Reviewed Literature

Luo et al. 2004

DOI: 10.1007/s00125-004-1495-3 →
Peer-Reviewed Literature

Pasi et al. 2022

DOI: 10.4103/jfmpc.jfmpc_975_21 →
Peer-Reviewed Literature

Mendis et al. 2023

DOI: 10.1016/j.bbrep.2022.101413 →
Peer-Reviewed Literature

Bhola et al. 2021

DOI: 10.1186/s12902-021-00812-8 →
Disclaimer: Educational synthesis of peer-reviewed literature only — not medical advice. Markers are drawn from published disease-vs-comparison-population studies; inclusion here does not imply diagnostic or clinical validation. Consult a qualified healthcare professional for interpretation.

Individual Type 1 Diabetes biomarker pages

Each Type 1 Diabetes marker has its own page with direction, comparison group, symptoms, test details, citation and FAQ. Browse all marker pages.

Metabolic

Cite this page

Reusing these data? Please cite the tracker so others can find the source.

Open Source Medicine Foundation. (2026). Type 1 Diabetes Biomarkers: 6 Blood Tests & Lab Markers. Research Tracker. https://research.opensourcemed.info/type-1-diabetes-biomarkers.html (accessed )

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