Peer-Reviewed Literature Synthesis

Type 1 Diabetes Biomarker Atlas

Molecular alterations reported in Type 1 Diabetes compared to healthy controls, from peer-reviewed literature.

Spontaneous remissionEssentially zero for established T1DM (honeymoon phase occurs in 50-60% after diagnosis but lasts 3-12 months then…
Best-intervention remissionClosed-loop insulin delivery (artificial pancreas systems — Control-IQ, Omnipod 5) achieves 70-80% time-in-range vs…
Gap sizeModerate-large — closed-loop approaches are increasingly standard but true insulin independence is rare with any…
Primary barrierbiological + access
Full remission profile →

Literature Overview

Biomarkers below are included only where peer-reviewed literature explicitly reports the marker's direction in Type 1 Diabetes patients relative to a named comparison population — not inferred.

6
Curated markers
1
Categories

Searchable Alterations Database

Comparison populations are quoted as reported in the source literature (e.g. healthy controls, disease-matched patients).

Marker / TestDirectionCategoryvs. ComparisonClinical ContextKey Reference

Key References

Peer-Reviewed Literature

Yu et al. 2019

DOI: 10.1172/JCI127397 →
Peer-Reviewed Literature

Yang et al. 2024

DOI: 10.1136/bmj-2023-078432 →
Peer-Reviewed Literature

Luo et al. 2004

DOI: 10.1007/s00125-004-1495-3 →
Peer-Reviewed Literature

Pasi et al. 2022

DOI: 10.4103/jfmpc.jfmpc_975_21 →
Peer-Reviewed Literature

Mendis et al. 2023

DOI: 10.1016/j.bbrep.2022.101413 →
Peer-Reviewed Literature

Bhola et al. 2021

DOI: 10.1186/s12902-021-00812-8 →
Disclaimer: Educational synthesis of peer-reviewed literature only — not medical advice. Markers are drawn from published disease-vs-comparison-population studies; inclusion here does not imply diagnostic or clinical validation. Consult a qualified healthcare professional for interpretation.

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