Summary
| Direction in Atrial Fibrillation | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Cardiac |
| Compared against | cardiac stress/AF vs healthy |
| Test type | Blood test (serum / plasma / whole blood) |
| LOINC code | 33762-6 |
| Source | Panagopoulou et al. 2013 — doi:10.2174/1568026611313020002 |
| Condition atlas | Atrial Fibrillation Biomarker Atlas |
Other conditions where NT-proBNP is reported
- NT-proBNP in Hypertension — ↑ elevated vs hypertensive (asymptomatic, at-risk) vs normal
- NT-proBNP in Long COVID — ↑ elevated vs HC
See the cross-condition hub: NT-proBNP across conditions.
Related Cardiac markers in Atrial Fibrillation
- D-dimer ↑
Full list: Atrial Fibrillation Biomarker Atlas.
Frequently asked questions
Is NT-proBNP high or low in Atrial Fibrillation?
Elevated. Studies summarised in the OSMF atlas report higher NT-proBNP in Atrial Fibrillation than in the reference group of the cited comparison (cardiac stress/AF vs healthy). Source: Panagopoulou et al. 2013.
Which test measures NT-proBNP?
It is measured as a blood test (serum / plasma / whole blood). The standard laboratory code is LOINC 33762-6. Many of the cited studies used research-grade assays, so clinical availability may vary.
Is one abnormal NT-proBNP result diagnostic of Atrial Fibrillation?
No. No single biomarker is diagnostic of Atrial Fibrillation. NT-proBNP findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
Is NT-proBNP specific to Atrial Fibrillation?
No. The same marker is also reported in Hypertension, Long COVID in this atlas, so it reflects shared biology (for example inflammation or vascular stress) rather than a condition-specific signature.
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Last reviewed: 2026-07-03 · Page generated from atrial-fibrillation.json · Browse: Atrial Fibrillation atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.