Peer-Reviewed Literature Synthesis

Atrial Fibrillation Biomarker Atlas

Molecular alterations reported in Atrial Fibrillation compared to healthy controls, from peer-reviewed literature.

US DALYs3.13MWHO GHE 2021 · all ages
Global DALYs28.29MWHO GHE 2021 · worldwide
US mortality109.5K deaths/yrWHO GHE 2021
Global mortality1.02M deaths/yrWHO GHE 2021 · worldwide
NIH funding$1.78BFY2025 · RCDC estimate
Funding levelWell-Funded
Spontaneous remissionSpontaneous reversion to sinus rhythm occurs in ~50% of paroxysmal AF within 24-48 hours; persistent AF almost never…
Best-intervention remissionCatheter ablation achieves freedom from AF in ~70-80% at 1 year (paroxysmal), 50-60% (persistent); ablation superior…
Gap sizeLarge — rate control vs rhythm control debate has shifted but practice hasn't caught up
Primary barrierpractice
Full remission profile →

Literature Overview

Biomarkers below are included only where peer-reviewed literature explicitly reports the marker's direction in Atrial Fibrillation patients relative to a named comparison population — not inferred.

8
Curated markers
3
Categories

Searchable Alterations Database

Comparison populations are quoted as reported in the source literature (e.g. healthy controls, disease-matched patients).

Marker / TestDirectionCategoryvs. ComparisonClinical ContextKey Reference

Key References

Peer-Reviewed Literature

Jabati et al. 2018

DOI: 10.1177/1076029618761006 →
Peer-Reviewed Literature

Rafaqat et al. 2024

DOI: 10.3390/biomedicines12020274 →
Peer-Reviewed Literature

Roldán et al. 1998

DOI: 10.1016/s0002-8703(98)70149-8 →
Peer-Reviewed Literature

Doulamis et al. 2019

DOI: 10.1093/icvts/ivy210 →
Peer-Reviewed Literature

Rivera-Caravaca et al. 2020

DOI: 10.1136/jim-2020-001351 →
Peer-Reviewed Literature

Oikonomou et al. 2019

DOI: 10.2174/0929867324666170830100424 →
Peer-Reviewed Literature

Sramko et al. 2019

DOI: 10.1007/s00392-018-1332-1 →
Peer-Reviewed Literature

Panagopoulou et al. 2013

DOI: 10.2174/1568026611313020002 →
Disclaimer: Educational synthesis of peer-reviewed literature only — not medical advice. Markers are drawn from published disease-vs-comparison-population studies; inclusion here does not imply diagnostic or clinical validation. Consult a qualified healthcare professional for interpretation.

Individual Atrial Fibrillation biomarker pages

Each Atrial Fibrillation marker has its own page with direction, comparison group, symptoms, test details, citation and FAQ. Browse all marker pages.

Cardiac

Inflammatory

Other

Cite this page

Reusing these data? Please cite the tracker so others can find the source.

Open Source Medicine Foundation. (2026). Atrial Fibrillation Biomarkers: 8 Blood Tests & Lab Markers. Research Tracker. https://research.opensourcemed.info/atrial-fibrillation-biomarkers.html (accessed )

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