Research Tracker›Biomarker Atlas›Type 2 Diabetes›Adiponectin

Adiponectin in Type 2 Diabetes

Adiponectin belongs to the metabolic group of Type 2 Diabetes markers and is reported to be decreased relative to the reference group of the cited comparison (T2DM/metabolic syndrome/CVD vs BMI-matched controls). The source does not tie this marker to a specific symptom cluster, so it is best read as a biological signal rather than a symptom predictor. The evidence summarised here comes from Fantuzzi et al. 2008 and reflects averages across cohorts rather than any single patient's result.

↓ ReducedMetabolic

Summary

Direction in Type 2 Diabetes↓ Reduced — lower than in the comparison group
CategoryMetabolic
Compared againstT2DM/metabolic syndrome/CVD vs BMI-matched controls
SourceFantuzzi et al. 2008 — doi:10.1016/j.jaci.2007.10.018
Condition atlasType 2 Diabetes Biomarker Atlas

Related Metabolic markers in Type 2 Diabetes

Full list: Type 2 Diabetes Biomarker Atlas.

Frequently asked questions

Is Adiponectin high or low in Type 2 Diabetes?

Reduced. Studies summarised in the OSMF atlas report lower Adiponectin in Type 2 Diabetes than in the reference group of the cited comparison (T2DM/metabolic syndrome/CVD vs BMI-matched controls). Source: Fantuzzi et al. 2008.

Which test measures Adiponectin?

The atlas record does not list a standardised clinical test code (LOINC) for Adiponectin, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal Adiponectin result diagnostic of Type 2 Diabetes?

No. No single biomarker is diagnostic of Type 2 Diabetes. Adiponectin findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). Adiponectin in Type 2 Diabetes: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/type-2-diabetes/adiponectin.html
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Last reviewed: 2026-07-02 · Page generated from type-2-diabetes.json · Browse: Type 2 Diabetes atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.