Salivary Pepsin: biomarker evidence

Salivary Pepsin appears in 1 entry of the OSMF biomarker atlas, covering GERD (Gastroesophageal Reflux Disease). Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

GERD (Gastroesophageal Reflux Disease)

Where Salivary Pepsin is reported

ConditionDirectionCompared againstAssociated symptomsSource
GERD (Gastroesophageal Reflux Disease)↑ elevatedGERD/hypersensitive esophagus patients vs asymptomatic healthy controls—Hayat et al. 2015

Frequently asked questions

In which conditions is Salivary Pepsin altered?

In the OSMF atlas Salivary Pepsin is reported in GERD (Gastroesophageal Reflux Disease). It is elevated in 1 across 1 entries.

Is there a standard clinical test for Salivary Pepsin?

The atlas entries for Salivary Pepsin do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Salivary Pepsin result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Salivary Pepsin across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/salivary-pepsin.html
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.