Summary
| Direction in Hypothyroidism | ↑ Elevated — higher than in the comparison group |
|---|---|
| Category | Endocrine |
| Also described as | Anti-Thyroglobulin |
| Compared against | autoimmune thyroiditis (Hashimoto's) patients vs healthy reference |
| Source | Dwivedi et al. 2023 — doi:10.1136/jcp-2022-208290 |
| Condition atlas | Hypothyroidism Biomarker Atlas |
Related Endocrine markers in Hypothyroidism
Full list: Hypothyroidism Biomarker Atlas.
Frequently asked questions
Is Anti-Thyroglobulin Antibodies high or low in Hypothyroidism?
Elevated. Studies summarised in the OSMF atlas report higher Anti-Thyroglobulin Antibodies in Hypothyroidism than in the reference group of the cited comparison (autoimmune thyroiditis (Hashimoto's) patients vs healthy reference). Source: Dwivedi et al. 2023.
Which test measures Anti-Thyroglobulin Antibodies?
The atlas record does not list a standardised clinical test code (LOINC) for Anti-Thyroglobulin Antibodies, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.
Is one abnormal Anti-Thyroglobulin Antibodies result diagnostic of Hypothyroidism?
No. No single biomarker is diagnostic of Hypothyroidism. Anti-Thyroglobulin Antibodies findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.
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Last reviewed: 2026-07-03 · Page generated from hypothyroidism.json · Browse: Hypothyroidism atlas · Biomarker Index · All marker pages
Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.