{
  "slug": "hypothyroidism",
  "id": "hypothyroidism-biomarkers",
  "condition": {
    "name": "Hypothyroidism",
    "shortName": "Hypothyroidism",
    "alternateNames": []
  },
  "page": {
    "title": "Hypothyroidism Biomarker Atlas | Blood Tests & Molecular Alterations",
    "breadcrumbName": "Hypothyroidism Biomarkers",
    "description": "Searchable atlas of Hypothyroidism biomarkers, from peer-reviewed literature comparing patient levels vs. healthy controls.",
    "keywords": [
      "Hypothyroidism biomarkers",
      "Hypothyroidism blood tests",
      "biomarker atlas",
      "biomarker database"
    ],
    "canonical": "https://research.opensourcemed.info/hypothyroidism-biomarkers.html",
    "hero": "Molecular alterations reported in Hypothyroidism compared to healthy controls, from peer-reviewed literature.",
    "dateModified": "2026-07-03"
  },
  "categories": {
    "endocrine": "Endocrine"
  },
  "filters": [
    "endocrine"
  ],
  "markers": [
    {
      "name": "Anti-Thyroglobulin Antibodies",
      "alternateName": "Anti-Thyroglobulin",
      "direction": "up",
      "category": "endocrine",
      "comparison": "autoimmune thyroiditis (Hashimoto's) patients vs healthy reference",
      "symptoms": "",
      "reference": {
        "citation": "Dwivedi et al. 2023",
        "doi": "10.1136/jcp-2022-208290"
      }
    },
    {
      "name": "Anti-TPO Antibodies",
      "alternateName": "Anti-TPO",
      "direction": "up",
      "category": "endocrine",
      "comparison": "autoimmune (Hashimoto's) hypothyroidism patients vs healthy reference",
      "symptoms": "",
      "reference": {
        "citation": "Kondramashin et al. 2021",
        "doi": "10.7759/cureus.17063"
      }
    },
    {
      "name": "Free T3",
      "alternateName": "Free T3",
      "direction": "down",
      "category": "endocrine",
      "comparison": "primary/overt hypothyroidism patients vs healthy reference range",
      "symptoms": "",
      "reference": {
        "citation": "Bhattacharyya et al. 2023",
        "doi": "10.1007/s12098-023-04578-w"
      }
    },
    {
      "name": "Free T4",
      "alternateName": "Free T4",
      "direction": "down",
      "category": "endocrine",
      "comparison": "overt hypothyroidism patients vs healthy reference range",
      "symptoms": "",
      "reference": {
        "citation": "McDermott 2020",
        "doi": "10.7326/AITC202007070"
      }
    },
    {
      "name": "TSH",
      "alternateName": "TSH",
      "direction": "up",
      "category": "endocrine",
      "comparison": "hypothyroidism patients vs healthy reference range",
      "symptoms": "",
      "reference": {
        "citation": "McDermott 2020",
        "doi": "10.7326/AITC202007070"
      }
    }
  ]
}