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Acetylcholinesterase (AChE): biomarker evidence

Acetylcholinesterase (AChE) appears in 1 entry of the OSMF biomarker atlas, covering Gulf War Illness. Across those entries it is mixed in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Gulf War Illness

Where Acetylcholinesterase (AChE) is reported

Also listed as: Cholinesterase

ConditionDirectionCompared againstAssociated symptomsSource
Gulf War Illness↕ inconsistenthealthy Gulf War veteran controlsPB/pesticide exposure sequelaeGean et al. 2021

Frequently asked questions

In which conditions is Acetylcholinesterase (AChE) altered?

In the OSMF atlas Acetylcholinesterase (AChE) is reported in Gulf War Illness. It is mixed in 1 across 1 entries.

Is there a standard clinical test for Acetylcholinesterase (AChE)?

The atlas entries for Acetylcholinesterase (AChE) do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Acetylcholinesterase (AChE) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Acetylcholinesterase (AChE) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/acetylcholinesterase-ache.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.