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Anti-OspA antibodies: biomarker evidence

Anti-OspA antibodies appears in 1 entry of the OSMF biomarker atlas, covering Lyme Disease. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Lyme Disease

Where Anti-OspA antibodies is reported

Also listed as: Outer surface protein A

ConditionDirectionCompared againstAssociated symptomsSource
Lyme Disease↑ elevatedUninfectedTick-borne transmission phaseLantos et al. 2021

Frequently asked questions

In which conditions is Anti-OspA antibodies altered?

In the OSMF atlas Anti-OspA antibodies is reported in Lyme Disease. It is elevated in 1 across 1 entries.

Is there a standard clinical test for Anti-OspA antibodies?

The atlas entries for Anti-OspA antibodies do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Anti-OspA antibodies result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Anti-OspA antibodies across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/anti-ospa-antibodies.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.