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CSF anti-Bb antibody index: biomarker evidence

CSF anti-Bb antibody index appears in 1 entry of the OSMF biomarker atlas, covering Lyme Disease. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Lyme Disease

Where CSF anti-Bb antibody index is reported

Also listed as: Intrathecal antibody production

ConditionDirectionCompared againstAssociated symptomsSource
Lyme Disease↑ elevatedSerum/CSF ratioNeuroborreliosis confirmationLantos et al. 2021

Frequently asked questions

In which conditions is CSF anti-Bb antibody index altered?

In the OSMF atlas CSF anti-Bb antibody index is reported in Lyme Disease. It is elevated in 1 across 1 entries.

Is there a standard clinical test for CSF anti-Bb antibody index?

The atlas entries for CSF anti-Bb antibody index do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal CSF anti-Bb antibody index result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). CSF anti-Bb antibody index across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/csf-anti-bb-antibody-index.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.