Research Tracker›Biomarker Atlas›Hypertension›High-Sensitivity CRP

High-Sensitivity CRP in Hypertension

In Hypertension, published studies report higher levels of High-Sensitivity CRP than in hypertensive participants without Apparent Treatment-Resistant Hypertension. Symptom domains tied to this marker in the source include apparent treatment-resistant hypertension in patients with chronic kidney disease. The finding is drawn from Chen et al. 2019; it describes group-level differences, not a threshold that classifies an individual.

↑ ElevatedInflammatory

Summary

Direction in Hypertension↑ Elevated — higher than in the comparison group
CategoryInflammatory
Compared againsthypertensive participants without Apparent Treatment-Resistant Hypertension
Associated symptomsApparent treatment-resistant hypertension in patients with chronic kidney disease
SourceChen et al. 2019 — doi:10.1161/HYPERTENSIONAHA.118.12358
Condition atlasHypertension Biomarker Atlas

Other conditions where High-Sensitivity CRP is reported

See the cross-condition hub: High-Sensitivity CRP across conditions.

Related Inflammatory markers in Hypertension

Full list: Hypertension Biomarker Atlas.

Frequently asked questions

Is High-Sensitivity CRP high or low in Hypertension?

Elevated. Studies summarised in the OSMF atlas report higher High-Sensitivity CRP in Hypertension than in hypertensive participants without Apparent Treatment-Resistant Hypertension. Source: Chen et al. 2019.

What symptoms is High-Sensitivity CRP associated with in Hypertension?

The cited literature associates this marker with Apparent treatment-resistant hypertension in patients with chronic kidney disease. These are population-level associations and do not mean the marker causes the symptoms.

Which test measures High-Sensitivity CRP?

The atlas record does not list a standardised clinical test code (LOINC) for High-Sensitivity CRP, which usually means it was measured with research assays or study-specific protocols rather than a routine clinical panel. Check the cited source for the exact method.

Is one abnormal High-Sensitivity CRP result diagnostic of Hypertension?

No. No single biomarker is diagnostic of Hypertension. High-Sensitivity CRP findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Is High-Sensitivity CRP specific to Hypertension?

No. The same marker is also reported in Migraine in this atlas, so it reflects shared biology (for example inflammation or vascular stress) rather than a condition-specific signature.

Cite this page

Open Source Medicine Foundation. (2026). High-Sensitivity CRP in Hypertension: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 8, 2026, from https://research.opensourcemed.info/biomarkers/hypertension/high-sensitivity-crp.html
Get OSMF research updates. New biomarker, trial and treatment evidence summaries by email.
Subscribe on Substack

Last reviewed: 2026-10-08 · Page generated from hypertension.json · Browse: Hypertension atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.