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High-Sensitivity CRP across conditions

High-Sensitivity CRP appears in 2 entries of the OSMF biomarker atlas, covering Hypertension, Migraine. Across those entries it is elevated in 1, mixed in 1. Because the same marker shifts in several unrelated conditions, it is best understood as a signal of shared biology such as inflammation, vascular or metabolic stress rather than as a condition-specific test. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

HypertensionMigraine

Where High-Sensitivity CRP is reported

ConditionDirectionCompared againstAssociated symptomsSource
Hypertension↑ elevatedhypertensive participants without Apparent Treatment-Resistant HypertensionApparent treatment-resistant hypertension in patients with chronic kidney diseaseChen et al. 2019
Migraine↕ inconsistentnon-migraineursmigraine without aura (MO) in women aged 19-34 years had borderline higher CRP; women aged 60-81 years with MO had significantly lower CRPGudmundsson et al. 2009

Frequently asked questions

In which conditions is High-Sensitivity CRP altered?

In the OSMF atlas High-Sensitivity CRP is reported in Hypertension, Migraine. It is elevated in 1, mixed in 1 across 2 entries.

Does High-Sensitivity CRP point to one specific diagnosis?

No. Because High-Sensitivity CRP changes in several conditions (Hypertension, Migraine), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.

Is there a standard clinical test for High-Sensitivity CRP?

The atlas entries for High-Sensitivity CRP do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal High-Sensitivity CRP result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). High-Sensitivity CRP across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 8, 2026, from https://research.opensourcemed.info/biomarkers/markers/high-sensitivity-crp.html
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Last reviewed: 2026-10-08 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.