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Transforming Growth Factor-β (TGF-β) across conditions

Transforming Growth Factor-β (TGF-β) appears in 2 entries of the OSMF biomarker atlas, covering Long COVID, ME/CFS. Across those entries it is elevated in 2. Because the same marker shifts in several unrelated conditions, it is best understood as a signal of shared biology such as inflammation, vascular or metabolic stress rather than as a condition-specific test. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Long COVIDME/CFS

Where Transforming Growth Factor-β (TGF-β) is reported

Also listed as: Fibrotic cytokine; Immunomodulatory cytokine

ConditionDirectionCompared againstAssociated symptomsSource
Long COVID↑ elevatedhealthy controls, recovered individuals without persistent symptomsPulmonary symptomsLai et al. 2023
ME/CFS↑ elevatedhealthy controlsImmune regulation, fibrosis signalingCorbitt et al. 2019

Frequently asked questions

In which conditions is Transforming Growth Factor-β (TGF-β) altered?

In the OSMF atlas Transforming Growth Factor-β (TGF-β) is reported in Long COVID, ME/CFS. It is elevated in 2 across 2 entries.

Does Transforming Growth Factor-β (TGF-β) point to one specific diagnosis?

No. Because Transforming Growth Factor-β (TGF-β) changes in several conditions (Long COVID, ME/CFS), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.

What is the LOINC code for Transforming Growth Factor-β (TGF-β)?

Entries in this atlas use LOINC 27999-4. LOINC codes identify the laboratory observation so results can be compared across systems.

Is one abnormal Transforming Growth Factor-β (TGF-β) result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Transforming Growth Factor-β (TGF-β) across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/transforming-growth-factor-beta-tgf-beta.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.