Where ALT is reported
Also listed as: Hepatic involvement; Liver enzymes (ALT/AST)
| Condition | Direction | Compared against | Associated symptoms | Source |
|---|---|---|---|---|
| Hepatitis C | ↑ elevated | acute/chronic HCV infection vs healthy reference range | — | Woo et al. 2024 |
| Lyme Disease | ↕ inconsistent | healthy controls | Disseminated Lyme subset | Lantos et al. 2021 |
| NAFLD / MASH (Metabolic-Associated Steatohepatitis) | ↑ elevated | NAFLD vs without NAFLD | — | Liu et al. 2023 |
Frequently asked questions
In which conditions is ALT altered?
In the OSMF atlas ALT is reported in Hepatitis C, Lyme Disease, NAFLD / MASH (Metabolic-Associated Steatohepatitis). It is elevated in 2, mixed in 1 across 3 entries.
Does ALT point to one specific diagnosis?
No. Because ALT changes in several conditions (Hepatitis C, Lyme Disease, NAFLD / MASH (Metabolic-Associated Steatohepatitis)), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.
Is there a standard clinical test for ALT?
The atlas entries for ALT do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.
Is one abnormal ALT result diagnostic?
No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas
Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.