Research Tracker›Biomarker Atlas›PACVS›Anti-AT1R (angiotensin II type 1 receptor)

Anti-AT1R (angiotensin II type 1 receptor) in PACVS

Anti-AT1R (angiotensin II type 1 receptor), also described as ATR1 autoantibody, belongs to the autoimmune group of PACVS (PACVS, PCVS) markers and is reported to be raised relative to healthy controls. Symptom domains tied to this marker in the source include lymphadenopathy, tonsillitis. The evidence summarised here comes from Mantovani et al. 2024 and reflects averages across cohorts rather than any single patient's result.

↑ ElevatedAutoimmune

Summary

Direction in PACVS↑ Elevated — higher than in the comparison group
CategoryAutoimmune
Also described asATR1 autoantibody
Compared againstHC (healthy controls)
Associated symptomsLymphadenopathy, tonsillitis
Test typeBlood test (serum / plasma / whole blood)
SourceMantovani et al. 2024 — doi:10.3390/biomedicines12122852
Condition atlasPACVS Biomarker Atlas

Trials, interventions and tests

Commercial test availability

Anti-AT1R Autoantibodies — specialty laboratory test.

Links are for reference only; availability, specimen requirements and coverage vary by location.

Related Autoimmune markers in PACVS

Full list: PACVS Biomarker Atlas.

Frequently asked questions

Is Anti-AT1R (angiotensin II type 1 receptor) high or low in PACVS?

Elevated. Studies summarised in the OSMF atlas report higher Anti-AT1R (angiotensin II type 1 receptor) in PACVS than in healthy controls. Source: Mantovani et al. 2024.

What symptoms is Anti-AT1R (angiotensin II type 1 receptor) associated with in PACVS?

The cited literature associates this marker with Lymphadenopathy, tonsillitis. These are population-level associations and do not mean the marker causes the symptoms.

Which test measures Anti-AT1R (angiotensin II type 1 receptor)?

It is measured as a blood test (serum / plasma / whole blood). Commercial laboratories such as CellTrend (specialty) list an orderable assay.

Is one abnormal Anti-AT1R (angiotensin II type 1 receptor) result diagnostic of PACVS?

No. No single biomarker is diagnostic of PACVS. Anti-AT1R (angiotensin II type 1 receptor) findings come from group comparisons, overlap considerably between patients and controls, and vary with study design, timing and comparison group. A result should be interpreted by a clinician alongside symptoms, history and other tests.

Cite this page

Open Source Medicine Foundation. (2026). Anti-AT1R (angiotensin II type 1 receptor) in PACVS: direction, evidence and what it means. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/pacvs/anti-at1r-angiotensin-ii-type-1-receptor.html
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Last reviewed: 2026-06-30 · Page generated from pacvs.json · Browse: PACVS atlas · Biomarker Index · All marker pages

Disclaimer: This page is an educational synthesis of published, peer-reviewed research and is not medical advice. Biomarker findings vary across studies with case definitions, comparison groups, timing and assay methods. Direction of change reflects the predominant finding in the cited source and does not establish a diagnostic threshold. Discuss any test result with a qualified clinician.