Interleukin-1 beta across conditions

Interleukin-1 beta appears in 2 entries of the OSMF biomarker atlas, covering Low Back Pain, Major Depressive Disorder. Across those entries it is elevated in 2. Because the same marker shifts in several unrelated conditions, it is best understood as a signal of shared biology such as inflammation, vascular or metabolic stress rather than as a condition-specific test. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

Low Back PainMajor Depressive Disorder

Where Interleukin-1 beta is reported

ConditionDirectionCompared againstAssociated symptomsSource
Low Back Pain↑ elevatedcontrol discs—Kang et al. 1996
Major Depressive Disorder↑ elevatedhealthy controls—Lorkiewicz et al. 2021

Frequently asked questions

In which conditions is Interleukin-1 beta altered?

In the OSMF atlas Interleukin-1 beta is reported in Low Back Pain, Major Depressive Disorder. It is elevated in 2 across 2 entries.

Does Interleukin-1 beta point to one specific diagnosis?

No. Because Interleukin-1 beta changes in several conditions (Low Back Pain, Major Depressive Disorder), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.

Is there a standard clinical test for Interleukin-1 beta?

The atlas entries for Interleukin-1 beta do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Interleukin-1 beta result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Interleukin-1 beta across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 8, 2026, from https://research.opensourcemed.info/biomarkers/markers/interleukin-1-beta.html
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Last reviewed: 2026-10-08 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.