Where S100B is reported
Also listed as: Astrocyte protein
| Condition | Direction | Compared against | Associated symptoms | Source |
|---|---|---|---|---|
| Epilepsy | ↑ elevated | epileptic patients vs healthy controls | — | Simani et al. 2020 |
| Gulf War Illness | ↕ inconsistent | healthy Gulf War veteran controls | Neurological symptoms subset | Gean et al. 2021 |
| Long COVID | ↑ elevated | healthy controls | Blood-brain barrier disruption | Baalbaki et al. 2025 |
Frequently asked questions
In which conditions is S100B altered?
In the OSMF atlas S100B is reported in Epilepsy, Gulf War Illness, Long COVID. It is elevated in 2, mixed in 1 across 3 entries.
Does S100B point to one specific diagnosis?
No. Because S100B changes in several conditions (Epilepsy, Gulf War Illness, Long COVID), an abnormal result cannot identify which condition, if any, is present. It must be interpreted with symptoms, history and other tests.
Is there a standard clinical test for S100B?
The atlas entries for S100B do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.
Is one abnormal S100B result diagnostic?
No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas
Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.