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Neutrophil elastase: biomarker evidence

Neutrophil elastase appears in 1 entry of the OSMF biomarker atlas, covering ME/CFS. Across those entries it is elevated in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

ME/CFS

Where Neutrophil elastase is reported

Also listed as: Protease

ConditionDirectionCompared againstAssociated symptomsSource
ME/CFS↑ elevatedhealthy controlsTissue damage, inflammationMaksoud et al. 2023

Frequently asked questions

In which conditions is Neutrophil elastase altered?

In the OSMF atlas Neutrophil elastase is reported in ME/CFS. It is elevated in 1 across 1 entries.

Is there a standard clinical test for Neutrophil elastase?

The atlas entries for Neutrophil elastase do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal Neutrophil elastase result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). Neutrophil elastase across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/neutrophil-elastase.html
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Last reviewed: 2026-06-29 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.