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FEV1/FVC ratio: biomarker evidence

FEV1/FVC ratio appears in 1 entry of the OSMF biomarker atlas, covering COPD. Across those entries it is reduced in 1. It is currently reported in a single condition in this atlas; cross-condition comparison will be added as the dataset grows. Each row below links to a page with the comparison group, associated symptoms, test details and primary citation.

COPD

Where FEV1/FVC ratio is reported

ConditionDirectionCompared againstAssociated symptomsSource
COPD↓ reducedCOPD-risk (passive smoking) vs non-exposed controls—Liu et al. 2025

Frequently asked questions

In which conditions is FEV1/FVC ratio altered?

In the OSMF atlas FEV1/FVC ratio is reported in COPD. It is reduced in 1 across 1 entries.

Is there a standard clinical test for FEV1/FVC ratio?

The atlas entries for FEV1/FVC ratio do not carry a LOINC code, which usually means the marker was measured with research assays or study-specific methods rather than a routine clinical panel.

Is one abnormal FEV1/FVC ratio result diagnostic?

No single biomarker result is diagnostic of any of these conditions. Findings reflect group averages from published cohorts with substantial overlap between patients and controls.

Cite this page

Open Source Medicine Foundation. (2026). FEV1/FVC ratio across conditions: biomarker evidence. OSMF Research Tracker. Retrieved October 7, 2026, from https://research.opensourcemed.info/biomarkers/markers/fev1-fvc-ratio.html
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Last reviewed: 2026-07-03 · Browse: Biomarker Index · All marker pages · Biomarker Atlas

Disclaimer: Educational synthesis of peer-reviewed research; not medical advice. Findings are group-level and vary with study design. Discuss any result with a qualified clinician.